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高压氧治疗新生儿缺氧缺血性脑病的临床价值 被引量:3

The clinical value of hyperbaric oxygen for neonatal hypoxic ischemic encephalopathy
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摘要 目的探讨高压氧治疗新生儿缺氧缺血性脑病的临床效果和价值。方法选择诊断为新生儿缺氧缺血性脑病(HIE)的新生儿96例,随机分为观察组和对照组,两组患儿均使用常规综合治疗,观察组在此基础上用高压氧辅助治疗,评估和对比两组患儿的治疗效果。结果在治疗前,两组的NBNA评分差异无统计学意义(t=0.114 5,P>0.05);疗程结束后,观察组的NBNA评分为(38.85±2.48)分,明显高于对照组(t=3.865 1,P<0.05)。观察组的总有效率为85.42%,明显高于对照组(χ2=9.882 4,P<0.05)。结论高压氧治疗对缺氧缺血性脑病的治疗效果显著,值得临床推广。 Objective To explore the clinical effect and value of hyperbaric oxygen for neonatal hypoxic ischemic en- cephalopathy. Methods Ninety-six cases of newborns with neonatal hypoxic ischemic encephalopathy (HIE) were selected and randomly divided into observation group and control group. Both groups were given conventional therapy while obser- vation group were also given hyperbaric oxygen. Then the treatment effectiveness of 2 groups were compared. Results Be- fore treatment, there was no statistical difference of NBNA score between two groups (t =0.114 5, P 〉 0.05); when the treatment was over, NBNA score of observation group was (38.85 ±2.48) scores, which was obviously higher than that of control group (t = 3.865 1, P 〈 0.05). The total effective rate of observation group was 85.42%, which was much higher than that of control group (x2 = 9.882 4, P 〈 0.05). Conclusion Hyperbaric oxygen has a great value for neonatal hypoxic is- chemic encephalopathy and is worthy of promotion.
作者 李珊 罗文燕
出处 《中国当代医药》 2012年第19期22-23,共2页 China Modern Medicine
基金 广东省深圳市卫生类科技计划项目(201103282)
关键词 高压氧 新生儿 缺氧缺血性脑病 临床效果 Hyperbaric oxygen Newborn Hypoxic ischemic encephalopathy Clinical effect
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