摘要
目的探讨直肠类癌的临床病理特点及影响预后的因素。方法回顾性分析31例直肠类癌患者的临床资料,所有病例均经手术和病理检查证实。将其按肿瘤直径大小和肌层是否有浸润分别分组,比较不同肿瘤直径各组和肌层是否浸润各组的手术治疗效果。结果本组31例直肠类癌患者的中位年龄49岁(22~83岁),中位随访时间36个月(15~86个月),随访率为80.6%(25/31)。随访期内,肿瘤直径≤l.0 cm的15例手术切除肿瘤后无复发,直径1.0~2.0 cm的7例中复发1例,直径>2.0 cm的3例中2例因类癌肝转移死亡。直肠类癌是否浸润肌层或全层以及是否有转移均与肿瘤大小有关(P<0.05);肿瘤的浸润深度与转移有关(P<0.05)。随着直肠类癌直径的增大,肿瘤浸润深度加深,转移发生率增高。结论直肠类癌的大小和肌层浸润可能是影响患者生存的重要因素,是选择手术方式时需参考的重要依据。
Objective To investigate the clinicopathological characteristics and factors influencing the prognosis of rectal carcinoid.Methods Clinical data of 31 cases with rectal careinoid,which identified diagnosis through operation and pathologic examination from January 2003 to March 2010 were retrospectively reviewed.Primary tumors were classified by size(≤1.0 cm,1.0-2.0 cm,and 〉2.0 cm)and muscularis invasion respectively,compared therapeutic effect of different groups.Results Median age of 31 cases was 49 years(22-83 years).Median follow-up time was 36 months(15-86 months),follow-up rate was 80.6%(25 /31).During the follow-up period,there were no cases with recurrence among the 15 patients with tumor size≤l.0 cm,1 case recurred in the 7 patients with turmor size between 1.0 cm to 2.0 cm,and 2 cases died from postoperative liver metastasis among the 3 patients with tumor size〉2.0 cm. There were relations between the tumor size,invasion depth,and metastasis(P〈0.05).Metastasis and invasion depth of tumor were possibility increment to follow the aggrandizement of the diameter of rectal carcinoid.Conclusion The diameter of rectal carcinoid and muscularis invasion may be important factors affecting survival,which may be an important basis for the choice of operative mode.
出处
《中国普外基础与临床杂志》
CAS
2012年第4期387-390,共4页
Chinese Journal of Bases and Clinics In General Surgery
关键词
直肠肿瘤
类癌瘤
病理学
临床
Rectal neoplasras; Carcinoid tumor; Pathology; Clinical