摘要
目的 :探讨胃幽门螺杆菌 (helicobacterpylori,Hp)感染与冠心病 (CHD)的关系。 方法 :对 62例CHD及 38例非冠心病 (non -CHD)心血管疾病患者血清进行Hp抗体检测。 结果 :CHD组和non -CHD组Hp抗体阳性率分别为 2 9 0 3 % (1 8/62 )和 31 58% (1 2 /38) ,两组无明显差异 (χ2 =0 0 73 ,P >0 0 5)。心功能Ⅰ～Ⅱ级组及Ⅲ～Ⅳ级组Hp抗体阳性率分别为 1 9 67% (1 2 /61 )和 46 1 5 % (1 8/39) ,两组有高度显著性差异 (χ2 =7 945 ,P <0 0 1 )。吸烟者与非吸烟者Hp抗体阳性率相比 (41 94%vs 2 4 64 % ) ,虽没有统计学差异 (χ2 =3 0 4 8,P >0 0 5) ,但有增高倾向。结论 :CHD患者Hp感染率未见增高 ,提示胃Hp感染与CHD无关。Hp感染与心脏病患者的心功能有关 ,心功能差的患者Hp感染率高。
Objective:To study the relation between helicobacter pylori (Hp) and coronary heart disease (CHD).Methods:Sera were assayed for Hp antibody in 62 patients with CHD and 38 patients with other cardiovascular diseases than CHD (non-CHD).Results:The Hp antibody positive rates of CHD group and non-CHD group were 29 03% (18/62) and 31 58% (12/38) respectively,there was no significant difference between the two groups (χ 2=0 073,P>0 05).The Hp antibody positive rates of NYHA function class Ⅰ～Ⅱ group and Ⅲ～Ⅳ group were 19 67%(12/61) and 46 15%(18/39) respectively,there was significant difference between the two groups (χ 2=7 945,P<0 01).The Hp antibody positive rate of smokers was higher than that of non-smokers (41 94% vs 24 64%),but there was no statistical significance (χ 2=3 048,P>0 05).Conclusions:The Hp infection rate of CHD patients doesn′t increase,it is suggested that the Hp infection is not relative to CHD.The Hp infection is relative to the heart function of CHD patients,the patients with low heart function have high Hp infection.The Hp infection rate of smokers has the tendancy of increasing.
出处
《中国冶金工业医学杂志》
2000年第1期6-7,共2页
Chinese Medical Journal of Metallurgical industry
关键词
幽门螺杆菌
冠心病
心功能
Helicobacter pylori Coronary heart disease Heart function
