摘要
目的分析某厂二硫化碳（CS2）作业人员健康状况，为采取预防措施提供依据。方法按照GBZ188-2007《职业健康监护技术规范》的要求对某厂881名CS2作业工人进行职业性健康体检。2008年该厂短丝车间CS2时间加权平均浓度（TWA）为55．3mg／m3，长丝车间为22．5mg／m3,分别是我国接触限值的10倍和4倍。据此，将长丝车间和短丝车间的工人归为高接触组，其余车间的工人归为低接触组。以881名CS2作业人员平均接触时间16年为界线，分为接触时间〈16年和接触时间≥16年组。结果881名CS2作业人员肢体麻木、乏力、头晕、失眠、头痛、浅感觉减弱、“三颤”（眼颤、手颤、舌颤）阳性、跟腱反射减退、膝反射减退和神经一肌电图异常的检出率分别为12．5％、8．5％、8．2％、7．5％、7．2％、33．0％、26．1％、20．8％、18．6％和10．8％，高血压、三酸甘油酯增高、低密度脂蛋白增高和载脂蛋白B增高的检出率分别为33．4％、24．5％、17．0％和9．3％。高接触组工人头晕、头痛、乏力、失眠、肢体麻木检出率在不同接触时间组间的差异有统计学意义（P〈0．05，P〈0．01）。高接触组接触工龄≥16年的工人跟腱反射减退、浅感觉、深感觉减弱、神经肌电图异常率高于接触时间〈16年的工人，低接触组接触时间≥16年工人的跟腱反射、浅感觉异常率高于接触工龄〈16年工人，差异均有统计学意义（P〈0．05，P〈0．01）。高接触组高血压患病率（30．7％）明显低于低接触组（38．1％），差异有统计学意义（P=0．027）。高接触组男性高血压、心动过缓和左心室高电压异常检出率明显高于女性；低接触组男性高血压检出率高于女性，差异均有统计学意义（P〈0．05，P〈0．01）。高接触组接触时间≥16年工人的总胆固醇、三酸甘油酯、低密度脂蛋白增高检出率高于接触�
Objective To study the effects of carbon disulfide （CS2） on the health of workers, and to provide the basis for the further preventive measures. Methods The occupational health examination of 881 workers exposed to CS2 in a chemical fiber factory was carried out according to the national technical standard of occupational health surveillance. The time weighted average concentrations （TWA） of CS2 in the workshops of short silk and long silk exceeded the national standard, The workers in these two workshops served as the high exposure group. The workers of the other workshops were classified as low exposure group, in which TWA met the national standard. All exposed workers were also divided into long-term exposure group and short-term exposure group on the basis of average exPosure years （16 years）. The statistical analysis was used by t test, X2, and fisher exact test. Results The symptom rates of numbness, fatigue, dizziness, insomnia and headache were 12.5%, 8.5%, 8.2%, 7.5%, and 7.2% respectively. The abnormal rates of superficial sensation, three fibrillation, achilles tendon reflex, patellar reflex, EMG, hypertension, triglycerides, low-density lipoprotein, and apolipoprotein B were 33.0%, 26.1%, 20.8%, 18.6%, 10.8%, 33.4%, 24.5%, 17.0% and 9.3% respectively. Among the high exposure group, the abnormal detectable rates of dizziness, headache, fatigue, insomnia, numbness, achilles tendon reflex, superficial and deep sensation, EMG, hypertension, ECG, total cholesterol, triglyceride and low density lipoprotein in long-term exposure group were significantly higher than those in short-term exposure group （P〈0.05 or P〈0.01 ）. However, among the low exposure group, the abnormal rates of the insomnia achilles tendon reflex and superficial sensation in long term exposure group were significantly higher than those of short term exposure group （P〈0.05 or P〈0.01）. The detected rates of hypertension, triglycerides, low-density lipoprotein, creatinine and uric acid were in males significantly g
出处
《中华劳动卫生职业病杂志》
CAS
CSCD
北大核心
2012年第6期443-447,共5页
Chinese Journal of Industrial Hygiene and Occupational Diseases
基金
江苏省优势学科建设工程资助项目（公共卫生与预防医学）
江苏省医学领军人才项目（LJ201130）
关键词
二硫化碳
职业暴露
神经病学表现
心血管系统
多项筛查
Carbon disulfide
Occupational exposure
Nervous manifestations
Cardiovascular system
