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磁共振三维增强肺动脉造影及其临床应用初步研究 被引量:2

Three-dimensional Dynamic Contrast-enhanced MR Pulmonary Angiography: Preliminary Experience of Clinical Application
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摘要 探讨核磁共振三维增强肺动脉造影成像技术及其临床应用价值。材料和方法:4例正常声愿者和12例怀疑肺动脉病变患者行3DDCE MRPA检查,成像序列为三维快速梯度回波(FFE-3D),主要参数为TR/TE:9/3ms,翻转角30°,矩阵128*256,快速注射0.2mmol/kgGd-DTPA,注射速度2mls,延迟时间正常组为5s,病变组依据病情而定,其中病变组经手术,血管造影和其他影像资料证实。 Purpose: to investigate the technique and clinical application of three-dimensional dynamic contrast-enhanced MR pulmonary angiography. Materials and Methods: A single breath-hold 3D DCE MRPA was performed in 4 volunteers and 12 patients of various pul monary diseases with 0. 2mmol/kg Gd-DTPA and 2ml/s injected rate by hand, and the delay time was determined on the basis of status of patients. Its sequences was FFE-3D (3D Fast Field Echo) with TR/TE: 9/3. ms, flip angle: 30°and Matrix: 128 × 156; Image quality was evaluated and its results of 3D DCE MRA were compared with angiography, operation and other imaging modalitis, then by student's statistics. Results: There were 15(93. 8 %) cases with excellent or good image quality in 16 cases; Main, left and right pulmonary artery, lobar and segmental artery displayed were 4, 4, 4, 20 and 64 in nomal group, and 11, 11, 11, 53 and 173 respectively(P > 0. 05 ) in abnomal group; 3D DCE MRPA accurately visulized location, size and degree of lesions of pulmonary artery and differentially diagnosed with other pulmonary diseases. Conclusion: 3D DCE MRPA Is an effective, minimally invasive method for displaying segmental and partial sub segmental artery, and of great potential in the evaluation of lesions of various pulmonary vascular diseases. It is still too early to predict wb6ther 3D DCE MRPA will routinely substitute IADSA for diagnosis, further clinical trails comparing 3D DCE MRPA with IADSA in a larger number of cases may be necessary.
出处 《中国医学影像学杂志》 CSCD 2000年第2期81-83,共3页 Chinese Journal of Medical Imaging
关键词 肺动脉 MRA 三维增强 血管造影术 Magnetic resonance imaging Contrast enhancement Pulmonary atrery Angiography
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