摘要
目的探讨高血压患者血压变异性、心率变异性与微量白蛋白尿之间的关系。方法选择高血压患者86例及健康人42例进行动态血压、动态心电图监测及尿微量白蛋白测定。结果两高血压组与B组比较,其不同时段平均收缩压、24h收缩压标准差及日间收缩压标准差差异有统计学意义(P<0.05);同时A2组不同时段平均,收缩压及24h收缩压标准差显著高于A1组及B组。两高血压组与B组比较,心率变异性降低;A2组减低程度明显高于A1组及B组。结论高血压患者存在机体自主神经功能受损,而合并有微量白蛋白尿者可加重自主神经功能紊乱。
Objective To investigate the rate variability （HRV） and microalbuminuria in relationships of blood pressure variability （ BPV）, heart patients with hypertension. Methods Eighty - six patients with hypertension and 42 healthy people were selected, ambulatory blood pressure monitoring, dynamic electrocardiogram and microalbuminuria were recorded and analyzed. Results Compared with control, the mean systolic blood pressure of different periods, 24 hours systolic blood pressure standard deviation （24hSBP- SD） and daytime systolic blood pressure standard deviation （dSBP- SD） were of significant difference between the two hypertension groups and control group; at the same time, mean systolic blood pressure and 24hSBP - SD of the microalbuminuria group （ group A2） were significantly higher than those of pure hypertension group （group A1 ） and the control group （ group B）. Compared with group B, heart rate variability of two hypertension groups decreased; moreover, that of group A2 reduced significantly higher than those of group A1 and group B. Conclusion The autonomic nervous system function are damaged in patients with hypertension, while the autonomic nervous disorders are aggravated when combined with mi^rn^lhnm;n,,r;~
出处
《河北医科大学学报》
CAS
2012年第4期379-382,共4页
Journal of Hebei Medical University
基金
河北医学科学研究重点课题计划项目(20100497)
关键词
高血压
血压
心率
白蛋白尿
hypertension
blood pressure
heart rate
albuminuria
