摘要
目的:了解嗜麦芽寡养单胞菌感染的临床分布及其耐药性变迁,为临床抗感染治疗提供依据。方法:回顾性分析本院各类临床标本中嗜麦芽寡养单胞菌的分离率、分布特点及药敏结果。结果:共检出嗜麦芽寡养单胞菌1902株,分离率为4.3%。标本来源以痰液为主,占93.2%;科室分布以重症监护室最多,占42.6%。该菌除对亚胺培南、庆大霉素等天然耐药外,对替卡西林、哌拉西林等也近乎完全耐药,对多粘菌素E、环丙沙星、替卡西林/棒酸等的耐药率达40%以上,而对头孢哌酮/舒巴坦、复方磺胺甲恶唑、米诺环素均保持较好的药物敏感性。结论:嗜麦芽寡养单胞菌感染呈逐年上升趋势,对多种抗菌药物完全耐药。
Objective：To investigate the distribution characteristics and drug resistance changes of Stenotrophomonas maltophilia,providing reference for clinical treatment.Methods： The isolation rate,distribution and drug resistance of Stenotrophomonas maltophilia isolated from various clinical specimens were retrospectively analyzed.Results： A total of 1902 strains of Stenotrophomonas maltophilia were isolated,the isolation rate was 4.3%.Sputum was the main specimen source（93.2%）.Stenotrophomonas maltophilia were mainly distributed at ICU,accounting for 42.6%.The result of drug sensitive test showed that the resistance rates of Stenotrophomonas maltophilia to imipenem and gentamicin were 100.0%.The drug-resistance rates of Stenotrophomonas maltophilia to ticarcillin and piperacillin were almost 100%,and to polymyxin E,ciprofloxacin,Ticarcillin/clavulanic were more than 40%.But it showed high sensitivity to cefoperazone/sulbactam,compound sulfamethoxazole and minocycline Stenotrophomonas maltophilia.Conclusion： Stenotrophomonas maltophilia infection rate was increasing year by year,and showed serious drug resistance to many kinds of antibiotics.
出处
《中国卫生检验杂志》
北大核心
2012年第5期1186-1188,共3页
Chinese Journal of Health Laboratory Technology
关键词
嗜麦芽寡养单胞菌
分布
耐药性
Stenotrophomonas maltophilia
Distribution
Drug resistance
