摘要
目的:研究骨髓增生异常综合征患者病态造血、外周血象与恶性克隆负荷的相关性。方法:回顾分析46例MDS患者,研究MDS骨髓病态造血、外周血象与恶性克隆负荷的相关性。结果:可见双核粒细胞、奇数核红细胞、粒细胞分叶不良与MDS高恶性克隆负荷显著相关(P<0.05);骨髓三系病态造血具有显著较高的克隆负荷(P<0.05);外周血出现幼稚粒细胞是高克隆负荷的指征(P<0.05)。结论:MDS高恶性克隆负荷的指标包括:双核粒细胞、奇数核红细胞、粒细胞分叶不良、三系病态造血、外周血出现幼稚粒细胞。
Objective：To investigate the correlation of dysplasia,peripheral blood and malignant clone load in patients with myelodysplastic syndrome.Methods： 46 MDS patients were selected for retrospective analysis.Results： Binucleated granulocyte,odd nucleated erythrocytes and granulocytes leaf dysplasia had significant correlation with high malignant clone load in MDS（P〈0.05）.RCMD was found have higher clone load（P〈0.05）.Immature granulocytes in peripheral blood was an indication of high clone load（P〈0.05）.Conclusion： MDS high malignant clone load indicators included binucleated granulocyte,odd nucleated erythrocytes,granulocytes leaf dysplasia,RCMD and immature granulocytes in peripheral blood.
出处
《中国卫生检验杂志》
北大核心
2012年第5期1078-1080,共3页
Chinese Journal of Health Laboratory Technology
基金
浙江省卫生厅(2011ZDA008)
杭州市科技局项目(20110833B53
20110833B42)资助
