摘要
冠心病是血管壁一种慢性炎性反应过程,冠状动脉内的炎性反应参与了动脉粥样硬化的全过程。炎性反应涉及多种炎性反应因子,目前已知的血清炎性因子,如可溶性细胞间黏附分子1、白细胞介素6、C反应蛋白、肿瘤坏死因子α、基质金属蛋白酶、核因子κΒ、组织因子、纤维蛋白原、同型半胱氨酸、脂蛋白(a)等,其在冠心病发生、发展过程中的作用已得到广泛认可。
Coronary heart disease is a chronic inflammatory reaction ot vessel wall,inflammatory reaction within the coronary artery participates in the whole process of atherosclerosis. Inflammatory response involvies a variety of inflammatory factors, currently known including serum inflammatory factors, such as ： soluble inter- cellular adhesion molecule-1 ,interleukin-6, C-reactive protein, tumor necrosis factor-a, matrix metalloprotein- ases, nuclear factor κB, tissue factor, fibrinogen, homocysteine, lipoprotein （ a）, etc. , the role of which in the development process of coronary heart disease has been widely recognized.
出处
《医学综述》
2012年第10期1467-1469,共3页
Medical Recapitulate
关键词
血清炎性因子
冠心病
斑块稳定性
Serum inflammatory factors
Coronary heart disease
Plaque stability
