摘要
坏疽性脓皮病(Pyoderma gangrenosum)是一种罕见而凶险的以皮肤坏疽性溃疡为特征的皮肤病,国内文献报道近20例,大多为个案报告,现将本院10年来收治的6例报告如下。
This article reports 6 cases of pyoderma gangrenosum of either acute or chronic clinical type. Etiologically, we found that minor local trauma could induce ulcerative and destructive lesions, with typical pyoderma gangrenosum features following in 4 cases.All the patients responded Well to systemic corticosteroids. In comparison with cases reported in other countries, no systemic diseases (including ulcerative colitis, Crohn's disease and polyarthritis) were found in our series. Cultures taken from early pustular lesions were sterile.Histopathological examination showed heavy neutrophilic infiltration in the dermis, and no evidence of vasculitis was found in the biopsies.Immunological investigations revealed no specific reactions in our cases.
出处
《中国医学科学院学报》
CAS
CSCD
北大核心
1990年第6期448-451,共4页
Acta Academiae Medicinae Sinicae
