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前列腺素E_2栓剂用于过期妊娠引产的临床研究 被引量:1

Clinical evaluation of Prostaglandin E_2 for induction in prolong pregnancy
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摘要 目的探讨前列腺素E2栓剂用于过期妊娠引产的疗效。方法将孕41周~41+6周、单胎、头位、未破膜的初产妇80例,随机分为研究组和对照组各40例,研究组阴道后穹窿放置前列腺素E2栓剂1枚,对照组微量泵应用催产素。观察并记录用药后6h宫颈评分改善情况、用药至临产所需时间、用药至分娩所需时间、24h引产成功率、胎儿、羊水情况。结果两组宫颈评分改善情况、引产成功率、临产和分娩所需时间比较差异均有统计学意义(P<0.05);而胎心异常和羊水粪染等方面无统计学差异(P>0.05)。结论普贝生相对于催产素用于延期妊娠引产更省时、成功率更高,且不增加分娩风险。 Objective To explore the effect of propess for the extension of labor induction.Methods The Prostaglandin E2 was used in 40 cases as study group,the oxytocin was ased in 40 cases as control group.All the pregnant women were single tire,and have not rupture of membranes,41-41+6weeks.They were randomly divided into PGE2 group and oxytocin group.The cervical score,24 h induction success rate,time to labor,cessrean section rate,fetal anmiotic fluid was observed and compared.Results The PGE2 could effectively and safely promote cervical ripening and increase the success rate of labor induction,which had short time-consuming,lower damage,and was more convenient and easier to be accepted by pregnant women and their families.There was not significant difference between 2 groups for fetal distress rate,postpartum hemorrhage rate.Conclusion Compared to the control group,the propess group had a higher success rate,and can reduce the cesarean section rate.
作者 于以莲 徐雷
出处 《中国实用医药》 2012年第11期41-42,共2页 China Practical Medicine
关键词 前列腺素E2栓剂 催产素 过期妊娠 PGE2 Oxytocin Prolong pregnancy
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  • 1乐杰..妇产科学[M].北京:人民卫生出版社,2008:4图版.
  • 2Ramsey PS, Owen J. Midtrimester cervical ripening and labor in- duction. Clin Obstet Gynecol,2000,43 (2) :495-512. 被引量:1
  • 3Strobalt N, Mergegalli V, Ratti M, et al. Randomized study on re- movable PGE2 vaginal insert versus PGE2 cervical gel for cervical priming and labor induetion in low Bishop score pegnaney. Acta Obstet Gynec Scand ,2006,85 ( 3 ) : 302 -305. 被引量:1
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