摘要
目的 :观察阿昔洛韦 (无环鸟苷 ,Aciclovir ,ACV)治疗小儿水痘的疗效。方法 :采用静脉滴注ACV及外用 3%ACV软膏治疗水痘患儿 36例 (1997～ 1999) ,并与利巴韦林静脉滴注及外用 1%甲紫的水痘患儿 35例(1995～ 1997)对照 ,观察两组疗效。结果 :治疗组明显优于对照组 ,差异显著 (χ2 =4.85 ,P <0 .0 5 )。结论 :通过静脉滴注ACV及外用 3%ACV软膏 ,可有效阻止水痘 带状疱疹病毒 (VZV)内脏传播 ,阻止VZV感染到真皮层 ,可明显缩短病程 ,安全有效。
To observe the curative effect of aciclovir (ACV) on chicken pox in children, the two different treatment methods were compared. From 1995 to 1997, 36 children, the two different treatment methods were compared. From 1995 to 1997, 36 children were subjected to intravenous perfusion of ACV plus external use of 3% ACV ointment 35 children were treated by intravenous perfusion Virazole plus external use of Gentian Violet. The curative effect ACV group is better than that of Virazole group, with the difference being statistically significant ( χ 2 = 4.85 , P < 0.05 ). The intravenous perfusion of ACV plus 3% ACV ointment for external use can prevent the chicken pox virus from spreading to internal organs and infecting the corium thereby shortening the disease course.
出处
《药物流行病学杂志》
CAS
2000年第1期5-6,共2页
Chinese Journal of Pharmacoepidemiology
关键词
陈昔洛韦
水痘
治疗
儿童
Chicken pox
Aciclovir
Clinical trial
