摘要
目的探讨后腹腔镜下供肾游离终末阶段,手辅助活体供肾切取术的安全性、实用性。方法回顾性分析2010年5月至2011年7月手辅助后腹腔镜下行活体供肾切取术16例资料,均取左肾。活体供肾关系为:父→子7例,母→子9例。供肾者年龄45—63岁,平均56岁;体质指数22.8~31.1kg/m^2,平均(26.3±2.4)kg/m^2。群体反应性抗体及淋巴细胞毒试验阴性。供肾者取右侧卧位,选3个穿刺点,经后腹腔游离供肾,于肋弓下第3个穿刺点为起点,沿11肋延长线走行方向延长切口长3—5cm,术者左手置入辅助,予Hem—o—lok夹闭动静脉并离断血管、输尿管,白手辅助切口取出肾脏。同时随机选取传统开放活体左侧供肾切取术16例进行对比。两种方法供肾植于受者髂窝。常规应用三联免疫抑制剂预防排斥反应。结果16例手辅助腹腔镜下供肾肾移植均获成功。手术时间70~150min,平均(101.3±21.2)min,出血量20~100ml,平均(53.8±25.5)ml,热缺血时间1.5~3.5min,平均(2.4±0.6)min,下床时间2~4d,平均(2.8±0.7)d。肾移植受者术后第1天尿量3500~6500ml,平均5036ml;SCr227~1170μmol/L,平均598μmol/L。术后1个月时平均SCr值为129μmol/L。肾移植后随访3~9个月肾功能正常。开放手术组手术时间85~115min,平均(95.8±10.5)min,手术出血量30—100ml,平均(65.4±23.7)ml,热缺血时间1.2—2.7min,平均(1.9±0.5)min,下床时间2~7(5.0±1.2)d。两组切口长度、术后下床时间比较差异有统计学意义(P〈0.05)。结论手辅助后腹腔镜下活体供肾切取术安全、对供体创伤小、对移植肾损伤小、可以获得更长的移植肾血管,与传统开放手术及腹腔镜取肾手术比较,具有较多优势。
Objective To evaluate the safety, feasibility and resuhs of the hand-assisted retroperitoneal laparoscopic living donor nephrectomy (HRPLDN) with a modified technique. Methods Living donors (n = 32) were divided into HRPLDN group (n = 16) and open group (n = 16) according to surgical technique. Operative data and postoperative outcomes including operative time, estimated blood loss, warm ischemia time, length of hospital stay and complication rate, were collected. Results All procedures were completed successfully. In HRPLDN group, the mean operative time was 101.3 ± 21.2 rain (range from 70 to 150 min) , with an estimated blood loss of 53.8 ± 25.5 ml (range from 20 to 100 ml) and warm ischemia time of 2.4 ± 0.6 min ( range from 1.5 to 3.5 min). No living donor needed conversion to open surgery and the urine volume of transplanted kidney after first 24 hours was 5036 ml (range from 3500 -6500 ml). The mean postoperative on bed time were (2.8 ±0.7) d (ranging from 2 -4 d). All parameters of HRPLDN were significantly better than that of open groups. Conclusion Living donor nephrectomy with HRPLDN is a safe and reliable surgical technique.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
2012年第6期426-428,共3页
Chinese Journal of Urology
关键词
腹腔镜
手辅助
肾移植
取肾术
Laparoscopy
Hand-assisted
Kidney transplantation
Nephrectomy