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表面增强拉曼光谱技术在肿瘤病理中的应用 被引量:4

Applications of Surface-enhanced Raman Spectroscopy in Tumor Pathology
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摘要 表面增强拉曼散射(Surface-enhanced Raman Scattering,SERS)技术作为鉴定生物分子种类最有力的分析工具之一,具有灵敏度高、特异性强、稳定性好及检测条件温和等优点。目前,SERS技术在肿瘤病理领域的应用尚处于起步阶段,但已显现出良好的应用前景和发展空间。该文简要介绍了SERS的机理、特性及活性基底,并对SERS技术在肿瘤病理的研究进展、局限性及潜在应用价值方面做较为全面的综述。 Surface-enhanced Raman scattering (SERS) technology is one of the most powerful analytical techniques for the identification of biological molecular species with high sensitivity, high specificity and good stability, as well as mild conditions of detection. At present, although SERS technique has been applied in tumor pathology in its infancy, SERS has shown good prospects and great potential. A brief introduction of the basic theory and common features of SERS and SERS active substrate, as well as recent advances and limitations of SERS in tumor pathology were presented here.
出处 《激光生物学报》 CAS CSCD 2012年第2期103-108,共6页 Acta Laser Biology Sinica
基金 国家自然科学基金项目(11104030 61178090 81101110)
关键词 表面增强拉曼散射(SERS) 肿瘤病理 超敏感检测 surface-enhanced Raman scattering (SERS) tumor pathology ultrasensitive detection
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  • 1RAMAN C, KRISHMAN K. A new type of secondary radiation [J]. Nature, 1928, 121(3048):501-502. 被引量:1
  • 2FLEISCHMANN M, HENDRA P, MCQUILLAN A. Raman spectra of pyridine adsorbed at a silver electrode [ J ]. Chemical Physics Letters, 1974, 26 (2) :163-166. 被引量:1
  • 3JEANMAIRE D L, VAN DUYNE R P. Surface Raman spectroelectrochemistry : Part I. heterocyclic, aromatic, and aliphatic amines adsorbed on the anodized silver electrode [ M ]. Journal of Electroanalytical Chemistry, 1977, 84 ( 1 ) : 1-20. 被引量:1
  • 4ALBRECHT M G, CREIGHTON J A. Anomalously intense Raman spectra of pyridine at a silver electrode [ J ]. Journal of the American Chemical Society, 1977, 99 (15) :5215-5217. 被引量:1
  • 5SMITH E, DENT G. Modem Raman spectroscopy:a practical approach[M]. Wiley, 2005:1-21, 113-133. 被引量:1
  • 6MOSKOVITS M. Surface-enhanced spectroscopy [ J]. Reviews of Modem Physics, 1985, 57 ( 3 ) :783-826. 被引量:1
  • 7OTTO A. Surface-enhanced Raman scattering: 'classical' and ' chemical' origins [ J]. Light Scattering in Solids IV, 1984, 54:289-418. 被引量:1
  • 8KNEIPP J, KNEIPP H, KNEIPP K. SERS-a single-molecule and nanoscale tool for bioanalytics [ J]. Chemical Society Reviews, 2008, 37 (5) : 1052-1060. 被引量:1
  • 9QIAN X, PENG X H, ANSARI D O, et al. In vivo tumor targeting and spectroscopic detection with surface-enhanced Raman nanoparticle tags [ J ]. Nature biotechnology, 2007, 26 ( 1 ) : 83 -90. 被引量:1
  • 10XIE W, QIU P, MAO C. Bio-imaging, detection and analysis by using nanostructures as SERS substrates [ J ]. Journal of Materials Chemistry., 2011, 21 : 5190-5202. 被引量:1

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