摘要
目的探讨动态监测血β-绒毛膜促性腺激素(β-hCG)水平在异位妊娠药物保守治疗中的预测价值。方法将88例初始血β-hCG≤3000U/L的异位妊娠患者随机分为A组和B组各44例,并按初始血β-hCG水平分为<1000U/L组(C组)38例和1000～3000U/L组(D组)50例。A组予以甲氨蝶呤、B组予以甲氨蝶呤联合米非司酮进行保守治疗。治疗期间动态监测所有患者血β-hCG水平,并进行临床疗效判定。结果所有患者共计治愈77例(87.50%)。B组临床治愈率为93.18%,高于A组的81.82%;C组临床治愈率为94.74%,高于D组的82.00%,差异均有统计学意义(P<0.05)。结论动态监测血β-hCG水平在异位妊娠药物保守治疗结局预测中具有一定临床意义。
Objective To investigate the predictive value of dynamic monitoring serum β-hCG in the medicine con- servative treatment for ectopic pregnancy. Methods 88 cases of ectopic pregnancy who＇s initial serum β-hCG≤3000U/L were randomly divided into group A and group B with 44 in each. According to the initial blood beta and hCG levels was 〈 by 1000U/L group（ group C ） in 38 patients and 1000 - 3000U/L group （group D ） in 50 cases. The group A was treated with methotrexate, group B was treated with methotrexate mifepristone combined conservative treatment. During treatment of dynamic monitoring in all patients serum beta and hCG levels, and clinical effect was observed. Results 77 cases were cured （87.50%）. Clinical cure rate in group B was 93.18% ,higher than that of group A（81.82% ） ; clinical cure rate in group C was 94. 74%, higher than the 82% in group D, and the differences were statistically significant （ P 〈 0.05）. Conclusion Dy- namic monitoring of serum β-hCG has some clinical significance in the outcome prediction of the medicine conservative treat- ment for ectopic pregnancy.
出处
《临床合理用药杂志》
2012年第14期37-38,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
异位妊娠
药物保守治疗
血Β-HCG
预测价值
Ectopic pregnancy
Conservative treatment
Serum beta and hCG
Predictive value
