摘要
目的探讨妊娠中期血抗心磷脂抗体(ACA)、血钙(Ca2+)、平均动脉压(MAP)检测对妊娠高血压综合征(PIH)的预测价值。方法对180例妊娠中期孕妇采用酶联免疫吸附法测定血ACA,自动生化分析仪检测血Ca2+水平,同时测量并计算MAP,对检测结果进行统计学分析。所有患者按检查结果分为PIH组和正常妊娠组。结果 PIH组血Ca2+水平低于正常妊娠组,差异有统计学意义(P<0.05)。以血ACA阳性、血Ca2+<2.20mmol/L、MAP≥85mmHg为联合预测指标,PIH阳性预测值为84.62%,阴性预测值为87.78%,敏感度为82.76%,特异度为97.04%,显著高于各单项检测的预测价值。结论妊娠中期联合检测血ACA、Ca2+、MAP对预测PIH具有较高的敏感性和特异性。
Objective To explore the clinical signifcance of middle pregnancy blood anticardiolipin antibodies （ACA） ,blood calcium（ Ca^2＋） ,mean arterial pressure（MAP） in prediction of the occurrence of pregnancy induced hyperten- sion（PIH）. Methods 180 cases of pregnant woman enrolled were selected. ACA was detected by enzyme-linked immunosor- bent assay and blood calcium was detected. Simultaneously, mean arterial blood pressure was measured. The data were ana- lyzed. Results The value of Ca^2＋ in the pregnant women with PIH was significantly lower than that in the normal pregnant women in pregnant 15 -20 week, Acording to ACA positive, Ca^2＋ （ 〈 2.20mmol/L, MAP ≥ 85 mm Hg）, Predictor of the three combined ,the positive predictive value of 84.62%, negative predictive value of 87.78%, sensitivity of 82.76% and specificity of 97.04 %. Conclusion The combined detection of mid-pregnancy blood ACA,blood calcium , mean arterial blood pressure have higher sensitivity and specificity.
出处
《临床合理用药杂志》
2012年第14期33-34,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
抗心磷脂抗体
血钙
平均动脉压
妊娠高血压综合征
预测价值
Anticardiolipin antibodies
Blood calcium
Mean arterial pressure
Pregnancy-induced hypertension
Pre-diction value
