摘要
目的观察中药熏蒸疗法治疗类风湿关节炎患者的疗效,对传统的中药熏蒸疗法治疗RA作出客观评价,进一步阐明中药熏蒸对RA的治疗机制。方法收集2009年2月至2011年3月在广州军区广州总医院中医科住院的RA患者60例,按照随机开放性原则将60例RA患者分为中药熏蒸组(熏蒸组)与非中药熏蒸组(非熏组),非熏组采用常规治疗,熏蒸组在常规治疗的基础上加中药熏蒸治疗。治疗1个疗程(20 d)之后,比较两组患者治疗前后和两组之间关节症状、体征、炎症指标[红细胞沉降率(ESR)、C-反应蛋白(CRP)]的变化情况。结果治疗20 d后两组疼痛VAS评分、关节肿胀度、压痛程度、关节疼痛数目、晨僵持续时间、关节屈伸度、局部温度、ESR、CRP均较治疗前有显著改善(P<0.01,P<0.05),熏蒸组在总有效率及达到ACR70改善的百分比上明显高于非熏组(P<0.01)。熏蒸组在患者的关节压痛程度、关节疼痛数、晨僵持续时间和关节局部温度的改善明显优于非熏治疗组(P<0.05),在关节肿胀度和关节屈伸度改善方面与非熏组差异无统计学意义(P>0.05)。疼痛VAS评分、ESR、CRP,熏蒸组下降明显(P<0.05)。结论中药熏蒸疗法治疗类风湿关节炎临床疗效显著,具有明显的抗炎消肿及镇痛作用。
Objective To evaluate the effect of the herb fumigation and steaming in treating rheumatoid arthritis（RA）,which will help to make an objective evaluation and clarify the mechanism of the therapy for RA.Methods 60 patients with RA who hospitalized from February 2009 to March 2011 in the department of Traditional Chinese Medicine of General Hospital of Guangzhou Military Area Command of Chinese PLA were collected.The cases were randomized divided into the herb fumigation and steaming therapy group（short for fumigation group） and the none herb fumigation and steaming therapy group（short for non-fumigation group）.Fumigation group was added the herb fumigation and steaming therapy on the basic of the conventional therapy.After one course of treatment（20 days）,we compared the changes of the patients＇ joint symptoms,signs,inflammatory index（erythrocyte sedimentation rate,C-reactive protein） before and after treatment between two groups.Results The total efficiency and the improvement of the percentage of ACR70 in Fumigation group were significantly higher than the non-fumigation group（P0.01）.The patient＇s joint tenderness,the frequency of joint pain,morning stiffness duration and joint local temperature in Fumigation group were significantly improved than non-fumigation group（P0.05）.There were no significant differences in joint swelling and improvement of joint flexion（P0.05）.VAS scores in pain,ESR and CRP in the two groups were significant different（P0.05）.Conclusion The herb fumigation and steaming therapy has an effective anti-inflammatory,relieving swelling and analgesic effect.
出处
《中国临床保健杂志》
CAS
2012年第2期113-116,共4页
Chinese Journal of Clinical Healthcare
基金
"十一五"国家科技支撑计划中医临床研究课题(2008BAI53B017)
关键词
关节炎
类风湿
蒸汽浴
中草药
Arthritis
rheumatoid
Steam bath
Drugs
Chinese herbal
