摘要
为了评价介入性肾动脉栓塞化疗(TACE)结合手术治疗肾母细胞瘤的有效性和可行性,回顾性分析我院收治的88例肾母细胞瘤患者的临床资料,分别采用术前行TACE治疗(研究组48例)和单纯手术治疗(对照组40例),评价肾母细胞瘤术前TACE的优缺点。TACE结合对照组在行TACE后44例患者的肿块明显缩小,平均缩小39.2%,且在手术切除肿瘤的包膜完整性(研究组40/48,对照组16/40)、肿瘤完全切除率(研究组48/48,对照组20/40)和术中出血量〔研究组(115.2±61.7)mL,对照组(220.8±105.3)mL〕方面,明显优于对照组。初步研究结果提示,肾母细胞瘤术前介入治疗能有效提高肿瘤的完整切除率,降低手术风险和复发的概率,有较高的临床应用价值。
The objective of this study was to estimate the effect and feasibility of trans-arterial chemoembolization （TACE） as a new preoperative treatment of Wilms＇ tumor. Clinical data of 88 cases with Wilms＇ tumor was retrospectively analyzed （study group： TACE with succedent surgery for 48 cases; control group： direct surgery for 40 cases） to evaluate the advantages and disadvantages of TACE before operation. Preoperative TACE significantly reduced the size tumor （44/48） with a average rate of 39.2 %, in the surgical removal of the tumor capsule integrity （TACE group 40/48, surgery only group 16/40） and complete tumor resection rate （TACE group 48/48, surgery only group 20/40）. Patients benefited more from TACE with succedent surgery than surgery alone, and the loss of blood was also significantly less than the surgery only group [（115.2±61.7） mL vs （220.8-}-105.3） mL]. In conclusion, preoperative TACE can significantly improve the rate of complete resection of the tumor and reduce surgical risk and recurrence rate, which demonstrate its great clinical value.
出处
《中华肿瘤防治杂志》
CAS
北大核心
2012年第7期543-544,546,共3页
Chinese Journal of Cancer Prevention and Treatment
关键词
肾母细胞瘤
介入治疗
栓塞
回顾性研究
nephroblastema
interventional treatment
embolization
retrospectire stadies
