摘要
目前乳腺癌已成为危害女性健康的第一大恶性肿瘤,且发病率呈逐年递增趋势,其早期诊断、治疗及预后成为当下研究的热点。乳腺癌肿瘤标志物对于其早期诊断、个体化治疗及预后均具有重要的临床实践指导意义。分子生物学的不断发展,为乳腺癌肿瘤标志物的基础与临床研究奠定了良好的基础。近年来,乳腺癌的诊断治疗手段逐渐增多,肿瘤标志物的应用也不断受到青睐,经典的肿瘤标志物已不足以更好的指导临床实践,因此不断有新的肿瘤标志物出现。为了解乳腺肿瘤标志物在乳腺癌诊治中的重要作用及其相关最新研究,本文结合国内外最新研究报道,对乳腺肿瘤标志物新的研究进展做一简要综述。
Breast cancer has become the first major female cancer that has increasingly threatened the health of women worldwide. The incidence of breast cancer has been reported to increase yearly. Thus, early diagnosis, individual treatment, and prognosis of breast cancer have currently been given more focus. Breast tumor biomarkers are significant guide for the early diagnosis, individual treatment, and prognosis of breast cancer. With the rapid development of molecular biology, very important foundations for basic and clinic research on breast cancer have been conducted. In recent years, various methods for the diagnosis and treatment of breast cancer have been proposed, and doctors who work in clinics daily have increasingly favored the use of breast tumor biomarkers. However, the use of classic tumor markers is insufficient in dealing with breast cancer. Thus, many studies constantly develop new biomaxkers to improve the techniques for the treatment and therapy of breast cancer, to relieve the pain of patients with breast cancer, and to reduce the social and personal economic burden. This article discusses the new developments on breast tumor biomarkers.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2012年第10期745-748,共4页
Chinese Journal of Clinical Oncology
关键词
乳腺肿瘤
肿瘤辅助疗法
肿瘤标记
Breast neoplasms
Neoadjuvant therapy
Tumor markers
