摘要
目的探讨本院药物不良反应(ADR)发生的特点、规律及相关诱发因素,为临床合理、安全用药提供指导依据。方法回顾性分析2008～2011年该院收集并成功上报国家药品不良反应监测中心的160例临床资料。结果引起不良反应合并用药21例(3.13%)、单一用药139例(86.87%)。以口服给药途径居首位,共110例(68.75%),其次为静脉滴注给药29例(18.13%),局部外用13例(8.13%),肌内注射6例(3.75%),阴道给药2例(1.25%)。结论药物不良反应的发生与诸多因素有关,应加强ADR的监测工作,注重并积极开展合理用药的宣传,减少ADR的发生率。
Objective To study the features,general patterns and predisposing factors of adverse drug reactions（ADR）occurred in our hospital and to provide the guidance basis for rational and safe use of drugs in clinic.Methods 160 cases of effective ADR reports collected from our hospital and reported to the National Center for ADR monitoring from 2008 to 2011 were analyzed retrospectively and statistically.Results ADR was caused by combination medication in 21 cases（3.13%） and single drug use in 139 cases（86.78%）.Oral administration in 110 cases（68.75%） topped the list,followed by intravenous drip in 29 cases（18.13%）,local external application in 13 cases（8.13%）,intra muscular injection in 6 cases（3.75%） and vaginal administration in 2 cases（1.25%）.Conclusion The occurrence of ADR is related with many factors.The ADR monitoring should be strengthened and the propaganda of rational drug use needs to be actively carried out to reduce the incidence of ADR.
出处
《重庆医学》
CAS
CSCD
北大核心
2012年第14期1407-1408,1423,共3页
Chongqing medicine
关键词
抗感染药
植物制剂
药品不良反应
分析
合理用药
非处方药
anti-infective agents
plant preparations
adverse drug reaction
analysis
rational use of drugs
over-the-counter（OTC） drugs
