摘要
目的了解昆明地区浅部致病真菌的分布情况。方法对本科2010年1月-2011年6月拟诊为浅部真菌病患者的临床标本再次进行镜检和分离培养及菌种鉴定,并对结果进行统计学分析。结果 7944份临床送验标本中,直接涂片镜检阳性率29.39%,培养阳性率19.70%,而镜检和(或)培养的阳性率为32.73%,显著高于单一的镜检或培养。上述3种方法的真菌检出率差异均有统计学意义(P均<0.005)。分离的1565株浅部致病真菌中,红色毛癣菌1088株(69.52%),马拉色菌216株(13.80%),须癣毛癣菌118株(7.54%)。镜检和(或)培养阳性的2600例浅部真菌病患者中,足癣803例(30.88%),甲真菌病424例(16.31%),股癣386例(14.85%),体癣364例(14.00%),花斑癣259例(9.96%),手癣194例(7.46%),马拉色菌毛囊炎83例(3.19%)和头癣46例(1.77%),同时患有手癣和足癣41例(1.58%)。结论镜检结合培养法的阳性率显著高于单一镜检或培养法,昆明地区浅部真菌的病种以足癣、甲真菌病、股癣较多见,浅部致病真菌以红色毛癣菌和马拉色菌为主。
Objective To investigate the etiologic distribution of pathogenic fungi in superficial mycoses in Kunming region.Methods Direct microscopy,culture and identification of pathogenic fungi were performed on clinical specimens.Results Among 7 944 specimens,the positive rate was 29.39% by direct microscopy and 19.70% by culture,while which by microscopy and（or） culture reached 32.73%.The detection rates had statistical differences among the three methods（P 〈 0.005）.T.rubrum,Malassezia and T.mentagrophytes among the 1 565 isolated pathogenic fungi strains were 69.52%,13.80% and 7.54%,respectively.The diseases were consisted of tinea pedis 30.88%,onychomycosis 16.31%,tinea cruris 14.85%,tinea corporis 14.00%,pityriasis versicolor 9.96%,tinea manus 7.46%,malassezia folliculitis 3.19%,tinea capitis 1.77%,tinea manus and pedis 1.58%.Conclusion The positive rate of microscopy combined with culture is significantly higher than that of single microscopy or culture.In Kunming region tinea pedis,onychomycosis,tinea cruris,tinea corporis gave priority to the kinds of disease of superficial mycosis.In the distribution of superficial pathogenic fungi,T.rubrum and Malassezia gave first place to the pathogen of superficial mycoses.更多还原
出处
《中国皮肤性病学杂志》
CAS
北大核心
2012年第6期501-503,共3页
The Chinese Journal of Dermatovenereology
关键词
浅部真菌病
病原真菌
Superficial mycoses
Pathogenic fungi
