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双侧睾丸精母细胞性精原细胞瘤1例并文献复习 被引量:4

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摘要 目的探讨睾丸精母细胞性精原细胞瘤(spermatocyticseminoma,SS)的临床病理学特征、诊断及鉴别诊断、治疗及预后。方法对1例双侧睾丸SS组织行EnVision两步法免疫组化染色,并复习相关文献。结果双侧睾丸肿瘤呈无痛性缓慢生长,组织学上肿瘤边界清楚,包膜完整,肿瘤细胞弥漫分布,黏附性差,由3种类型细胞组成,缺少淋巴细胞浸润及间质肉芽肿反应。免疫表型:肿瘤细胞CD99、CD117、BCL-2阳性,CK、CD3、CD7、CD20、CD30、inhibin、PLAP、CK18均阴性,Ki-67增殖指数为50%。结论 SS是一种罕见的睾丸肿瘤,与经典性精原细胞瘤的临床及病理特点均不同,好发于老人,双侧发生者更为罕见。其与经典性精原细胞瘤、胚胎性癌和淋巴瘤鉴别非常重要,单纯睾丸切除后不需进一步治疗,预后良好。
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2012年第5期583-585,共3页 Chinese Journal of Clinical and Experimental Pathology
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参考文献15

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