摘要
噬菌体裂解酶是噬菌体在感染细菌后期表达的一类细胞壁水解酶,具有酶活性和底物特异性。多数噬菌体具有编码3种细胞壁水解酶即溶菌酶、酰胺酶和内肽酶的基因。本文综述了噬菌体裂解酶重组及其应用的研究,并探讨了近年来重组裂解酶的研究进展。
Bacteriophage lysins are cell wall lytic enzymes expressed in the late phase of bacterial infection, with enzyme activity and substrate specificity. Most of bacteriophages contain the genes encoding three kinds of eell wall lyric enzymes, i.e. lysozyme, N-acetylmuramoyl-L-alanine amidase and endopeptidases. This paper reviews the recombination and application of bacteriophage lysins as well as the progress in research on recombinant lysins in recent years.
出处
《中国生物制品学杂志》
CAS
CSCD
2012年第5期657-660,共4页
Chinese Journal of Biologicals
