摘要
目的探讨前列地尔综合治疗高脂血症性急性胰腺炎的临床疗效。方法临床收集85例高脂血症性急性胰腺炎患者,按照病人药物应用情况分成两组,对照组45例,予以传统的禁食、胃肠减压、奥曲肽、奥美拉唑治疗;治疗组40例,在对照组治疗措施的基础上加用前列地尔,疗程为5～10 d。评价两组方法的临床疗效。结果与对照组相比较,治疗组的临床症状、体征、血淀粉酶转阴时间及总有效率具有统计学差异(P<0.05)。结论在使用奥曲肽、奥美拉唑的基础上加用前列地尔的综合疗法可以缩短病程有效治疗高脂血症性急性胰腺炎,值得临床推广应用。
Objective To investigate the clinical effects of Alprostadil combined with comprehensive treatment for hyperlipidemia acute pancreatitis.Methods Totally 85 patients with hyperlipidemia acute pancreatitis were studied and divided into control（n=45） and experiment group（n=40） according to the administration of drugs.The patients in control group were received traditional treatment（fasting,gastric intestinal decompression,Omeprazde,Octreotide） while those in experiment were given Alprostadil（5~10 days） combined with traditional treatment.The clinical efficacy in the two groups was compared after the therapy.Results There were marked differences between the two groups in clinical symptom,total effective rate,signs and time for serum amylase to turn negative after the therapy（P0.05）.Conclusion Alprostadil combined with Omeprazde and Octreotide is effective in reducing the disease duration for patients with hyperlipidemia acute pancreatitis and it is worth promoting in clinics.
出处
《局解手术学杂志》
2012年第3期303-304,共2页
Journal of Regional Anatomy and Operative Surgery
关键词
急性胰腺炎
前列地尔
综合治疗
临床疗效
acute pancreatitis
Alprostadil
comprehensive treatment
clinical effect
