摘要
目的本研究尝试LABVIEW在神经电生理学仿真方面的新应用，运用LABVIEW对轴突兴奋特性进行仿真。方法使用LABVIEW模拟乌贼巨型轴突的各种兴奋特性，包括阈值、不应期、时间整和效应、阳极阻断兴奋、适应性及传导速度。结果LABVIEW程序准确地描述了Na＋和K惨透率的变化以及他们对动作电位的影响，膜兴奋特性得到了很好的预测。结论LABVIEW图形化的编程语言使用户只需进行简单的拖放和连线操作即可完成编程，使用者可以方便快速地构建自己的生物学系统。
Objective In this paper a new application of LABVIEW in neural electrophysiological simulation was applied to simulate axonal excitability. Methods A variety of axonal excitability of the squid giant axon was modeled with LABVIEW, including action potential threshold, refractoriness, temporal summation, anode break excitation, repetitive firing and conduction velocity. Results The LABVIEW program accurately described the permeability changes of Na＋ and K＋ and their effects on the action potential, and the membrane excitability had been well predicted. Conclusion The graphical programming language of LABVIEW allows the user to complete the programming by dragging and dropping icons and connecting wires, the users can quickly and easily construct their own biological research systems.
出处
《国际生物医学工程杂志》
CAS
2012年第2期97-99,115,I0010,F0003,共6页
International Journal of Biomedical Engineering
基金
国家自然科学基金资助项目（30870649）
