期刊文献+

不同剂量艾司洛尔用于无痛胃肠镜镇静麻醉和麻醉复苏的临床研究 被引量:19

下载PDF
导出
摘要 目的:研究艾司洛尔在无痛胃肠镜镇静麻醉和麻醉复苏中的合理用量。方法:120例择期在丙泊酚-瑞芬太尼静脉麻醉下行无痛胃肠镜检查的门诊患者,年龄18~55岁,ASAⅠ~Ⅱ级,随机分为3组,每组40例:C组为对照组;E1组为0.5mg/kg的艾司洛尔组;E2组为1.0mg/kg的艾司洛尔组。两组麻醉诱导及维持药物均为丙泊酚和瑞芬太尼。观察丙泊酚-瑞芬太尼总量;BIS﹑HR、MAP、SpO2的变化;不良反应;检查后5min警觉/镇静评分(OAA/S评分);患者达到离院标准的时间。结果:C组丙泊酚用量(3.2±0.3)mg/kg、瑞芬太尼(0.4±0.0)μg/kg明显多于E1[(2.1±0.2)mg/kg、(0.3±0.0)μg/kg]、E2[(2.0±0.2)mg/kg、(0.3±0.1)μg/kg]组(P<0.05);HR、MAP、BIS的变化C组与E1、E2组及基础值比较显著升高(P<0.05);E1组与基础值比较升高明显(P<0.05),E2组与C、E1组及基础值比较显著降低(P<0.05);术毕5min OAA/S评分中C组清醒时间(5.3±0.0)min明显低于于E1[(2.6±0.0)]min、E2[(2.5±0.1)min]组;C组留观时间(50.1±6.5)min显著长于E1[(30.2±6.5)min]、E2[(30.4±5.9)min]组(P<0.05)。结论:艾司洛尔联合应用于无痛胃肠镜的镇静麻醉中能减轻伤害性刺激的应激反应,其合理用量为1.0mg/kg,并能减少麻醉药用量,缩短麻醉复苏时间。
出处 《实用医学杂志》 CAS 北大核心 2012年第9期1524-1526,共3页 The Journal of Practical Medicine
  • 相关文献

参考文献11

  • 1徐淑峰.艾司洛尔复合异丙酚缓解气管插管时应激反应的剂量水平的调查分析[J].中国医学创新,2010,7(6):13-15. 被引量:4
  • 2乔庆,顾晓静,徐静,钟泰迪.艾司洛尔应用于门诊手术的镇静麻醉中对脑电双频指数和麻醉复苏的影响[J].中华医学杂志,2010,90(23):1631-1634. 被引量:8
  • 3安刚,薛富善主编..现代麻醉学技术[M].北京:科学技术文献出版社,1999:1471.
  • 4Rudner R, Jalowiecki P, Kaweeki P, et al. Conscious analgesia/sedation with remifentanil and propofol versus total intravenous anesthesia with fentanyl, midazolam, and propofol for outpatient colonoscopy [J]. Gastrointest Endosc, 2003,57 (6) :657-663. 被引量:1
  • 5Sintetos A L, Hulse J, Pritchett El. Pharmacokineties and pharmacodynamics of esmolol administered as intravenous bolus [J]. Clin Pharmacol Ther, 1987,41(1):112-117. 被引量:1
  • 6Robert N S, Kaven J K. Labetalol for the control of elevated blood pressure following coronary artery bypass grafting [J]. Cardiothoras Anesth, 1990,4 (2) : 210-221. 被引量:1
  • 7姚兰,于德水,金清尘,王天龙,施英,田伟,赵华.不同剂量艾司洛尔复合异丙酚对气管插管时应激反应的影响[J].中华麻醉学杂志,2001,21(4):210-212. 被引量:25
  • 8Davidson E M, Doursout M F, Szmuk P, et al.Antinociceptive and cardiovascular properties of esmolol following formalin injection inrats [J]. Can J AnaMth, 2001,48( 1 ) :59-64. 被引量:1
  • 9Berridge C W, Foote S L. Enhancement of behavioral and electmencephalographic indices of walking following stimulation of noredrenergic beta receptors within the media septal region of the basal forebrain [ J]. J Neurosci, 1996,16 (21 ) : 6999-7009. 被引量:1
  • 10Yoo C W, Jeong M W. Bispectral index values during sevofluraneitrous oxide general anesthesia in women undergoing cesarean delivery:a comparison between women with or without priorlabor [J]. Anesth Analg, 2008,106(6) : 1827-1832. 被引量:1

二级参考文献29

  • 1王尔华,周路阳,吴浩,陈洁,朱炜,马正良.艾司洛尔对子宫切除术麻醉及术后镇痛的影响[J].临床麻醉学杂志,2006,22(6):470-471. 被引量:2
  • 2Oda Y,Nishikawa K,Hase I.The short-acting betal ndrenoceptor antagonists esmoiol and landiolol suppress the bispectral index response to tracheal intubation during sevoflurane anesthesia.Anesth Analg,2005,100:733-737. 被引量:1
  • 3Masaki E.Antinocicoptive effects of landiolol and esmolol.Masui,2006,55:849-855. 被引量:1
  • 4Johansen JW.Esmolol promotes electroencephalographic burst suppression during propfol/alfentanil anesthesia.Anesth Aanlg,2001,93:1526-1531. 被引量:1
  • 5Chia YY,Chan MH,Ko NH,et al.Role of beta-blockade in anaesthesia and postoperative pain management after hysterectomy.Br J Anaesth,2004,93:799-805. 被引量:1
  • 6Ozturk T,Kaya H,Aran G.Postoperative beneficial effects of esmolol in treated hypertensive patients undergoing laparoscopic cholecystectomy.Br J Anaesth,2008,100:211-214. 被引量:1
  • 7White PF,Wang B,Tang J,et al.The effect of intraoperative use of esmolol and nicardipine on recovery after ambulatory surgery.Anesth Analg,2003,97:1633-1638. 被引量:1
  • 8Scott I,Marshall FRCA,Frances C,et al.Discharge Criteria and Complications After Ambulatory Surgery.Anesth Analg,1999,88:508-517. 被引量:1
  • 9Kawaguchi I,Takamatsu K,Masui T,et al.Effect of landiolol on bispectral index and spectral entropy responses to tracheal intubation during pmpofol anaesthesia.Br J Anaesth,2008,101:273-278. 被引量:1
  • 10Wilson ES,McKilay S,Crawford JM,et al.The influence of esmolol on the dose of propofol required for induction of anaesthesia.Anaesthesia,2004,59:122-126. 被引量:1

共引文献32

同被引文献106

  • 1全剑锋.无痛胃肠镜镇静麻醉和麻醉复苏中应用不同剂量艾司洛尔的临床观察[J].临床研究,2014,22(8):76-77. 被引量:3
  • 2岑伟.简易精神状态检查法与修订的长谷川痴呆量表的临床应用[J].神经病学与神经康复学杂志,2006,3(4):207-209. 被引量:20
  • 3高敏,陆志俊.不同剂量艾司洛尔对老年冠心病患者BNP和NT-proBNP水平的影响[J].中国老年学杂志,2014,34(3):610-612. 被引量:4
  • 4郭曲练,姚尚龙.主编.临床麻醉学.3版.北京:人民卫生出版社.2011:132-342. 被引量:5
  • 5Ladas S D, Novis B, Triantafyllou K, et al. Ethical issues inendoscopy: patient satisfaction, safety in elderly patients, palliation, andrelations with industry. Second European Symposium on Ethics in Gastroenterology and Digestive Endoscoy, Kos, Greece, July 2006 [J]. Endoscopy, 2007,39 (6) :556-565. 被引量:1
  • 6Rudner R, Jalowiecki P, Kawecki P, et al. Conscious analgesia/sedation with remifentanil and propofol versus total intravenous anesthesia with fentanyl, midazolam, and propofol for outpatient colonoscopy [J]. Gastrointest Endosc, 2003,57 (6) :657-663. 被引量:1
  • 7Padmanabhan U, f,eslie K, Eer A S, et aL Early cognitive impairment after sedation for colonoscopy: the effect of adding midazolam and/or fentanyl to propohl [J]. Anesth Analg, 2009, 109(5):1448-1455. 被引量:1
  • 8Amomyotin S, Chalayonnawin W, Kongphlay S. Deep sedation for endoscopic retrograde eholangiopancreatography: a comparison between clinical assessment and Narcotrend TM monitoring [J]. Med Devices: Evid Res, 2011,4(3) :43-49. 被引量:1
  • 9Maria Laura Annunziata, Renato Caviglia, Luigi Giovanni Papparella, et al. Upper Gastrointestinal Involvement of Crohn's Disease: A Prospective Study on the Role of Upper Endoscopy in the Diagnostic Work-Up[J].Digestive Diseases and Sciences,2012,57(6): 1618-1623. 被引量:1
  • 10钱家鸣.消化内科学.2版.北京:人民卫生出版社,2015:321-323. 被引量:1

引证文献19

二级引证文献109

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部