摘要
目的 探讨苏州市儿童功能性消化不良（FD）流行病学特点及与幽门螺杆菌（HP）感染的关系,指导临床诊治.方法 横断面调查苏州市沧浪区12,923名在校小学生,初筛出有上腹痛（EPS）及餐后不适（PDS）症状的患儿,再由消化专科医师问卷调查,按照罗马Ⅲ标准诊断FD,进行13C呼气试验检测HP,阳性者予根除治疗.结果 1.FD总的患病率为8%,其中餐后不适患病率为3%,上腹痛患病率为5%.2.各年龄组小学生餐后不适患病率差异有统计学意义（P＜0.05）,上腹痛患病率差异无统计学意义（P＞0.05）.3.餐后不适男生患病率为3.2%,女生2.8%,差异无统计学意义（P＞ 0.05）;上腹痛男生患病率为4.5%,女生5.7%,差异有统计学意义（P＜0.01）.4.FD患儿HP感染率为27.3%,FD患儿在不同亚型的HP感染率差异无统计学意义.5.FD患儿就诊率87.9%,有病假记录者占46.8%.结论 FD是儿童时期消化系统的常见病,以上腹痛多见.HP感染与FD发病有关,其机制有待进一步研究.FD患儿就诊率高,影响生活质量,应引起儿科医师的足够重视.
Objective To investigate the epidemiology of functional dyspepsia and the relation between functional dyspepsia and HP infection among children in Suzhou to direct clinical treatment.Methods We cross-sectionally surveyed 12,923 pupil in Canglang district of Suzhou city, prescreened the children with epigastric pain and postprandial distress,diagnosed functional dyspepsia according to Rome III definition by questionnaire,detected HP by 13C breath test,and treat the patients with HP infection.Results 1.Prevalence of FD is 8% in 12,923 pupil,prevalence of PDS is 3%,prevalence of EPS is 5%.2.In different age groups,prevalence of PDS has statistical significance but prevalence of EPS has no statistical significance.3.Prevalence of PDS in boys is 3.2%,it is 2.8% in girls.There is no statistical significance.Prevalence of EPS in boys is 4.5%,it is 5.7% in girls. There is statistical significance.4.Infection rate of HP is 27.3% in FD.There is no statistical significance between PDS and EPS.Conclusion FD is a common disease in children, prevalence of FD is 8% in Suzhou.HP infection is likely to a etiological factor in development of FD,but the Pathogenesis need more research.
出处
《中国血液流变学杂志》
CAS
2012年第1期115-118,139,共5页
Chinese Journal of Hemorheology
