摘要
酿酒酵母的细胞衰老研究作为生命科学领域的前沿课题,对解析高等真核生物衰老的分子机制具有重要意义。迄今为止,在酵母中已经确立的衰老模式有两种,即复制型衰老和时序型衰老。细胞衰老的影响因子较多,涉及到很多过程,所以研究起来非常复杂。综述了两种细胞衰老机制的研究进展。
As the new frontiers in life science, studies on mechanisms of aging in Saccharomyces cerevisiae have important reference meaning to uncover molecular mechanisms of aging in higher eukaryotes. So far, there are two aging model have been established, replication aging and chronological aging. Moreover, there are many affecting factors to cell aging. The study on cell aging is very complicated. Here, the progress on molecular mechanisms of two different aging models was reviewed.
出处
《生物学杂志》
CAS
CSCD
2012年第2期69-72,共4页
Journal of Biology
基金
国家自然科学基金项目(No.50978208)
关键词
酿酒酵母
衰老
分子机制
Saccharomyces cerevisiae
aging
molecular mechanisms
