摘要
目的探讨前颅底中线区大型脑膜瘤的显微外科治疗。方法应用显微外科手术治疗17例前颅底中线区大型脑膜瘤。采用单额开颅经纵裂入路10例，双额开颅额下入路7例。结果根据脑膜瘤切除Simpson分级，肿瘤全切除（SimpsonI、Ⅱ级）14例，近全切除3例。结论单额开颅经纵裂人路和双额开颅额下入路都能够达到全切除前颅底中线区大型脑膜瘤的目的，前者经单侧额部入路，术中仅影响单侧额叶，术后脑组织损伤较后者轻，且可能保留一侧嗅神经。单额开颅经纵裂人路优于双额开颅。
Objective To investigate the clinical effect of microsurgical treatment of large meningion^as in median region of anterior skull base. Methods 17 patients were given microsurgical resection through two different operative approaches, including 10 cases through the coronal incision unilateral interhemispheric approach and 7 coronal incision transcranial subfrontal bilateral approach. Results According to Simpson grades of meningioma resection, total resection （Simpson grade I and 1I） was achieved in 14 cases, and subtotal resection in 3. Conclusions Total resection of large meningiomas in the median region of anterior skull base could be achieved through the beth approaches. The operative injury of unilateral interhemispheric approach is much more slight because only the unilateral frontal lobe is pulled and the contralateral olfactory nerve could be reserved intact. So the unilateral interhemispheric approach might be more suitable for median region of anterior skull base than the bilateral trans -subfrontal approach.
出处
《中华神经外科杂志》
CSCD
北大核心
2012年第4期372-374,共3页
Chinese Journal of Neurosurgery
关键词
大型脑膜瘤
前颅底
显微外科手术
手术入路
Large meningiomas
Anterior skull base
Microsurgery
Operative approach
