摘要
种植体周围炎是指发生在正常行使功能的骨性结合种植体周围组织的炎症,它是引起种植体失败的主要原因。种植体周围炎在临床上表现为种植体周围流脓或者探诊出血、瘘管、牙龈退缩,X线片示种植体周围有骨丧失。引起种植体周围炎的因素很多,包括微生物、生物力学负载过重、患者基因易感性、有牙周炎病史和吸烟史都会增加种植体周围炎的风险。大部分学者认为:吸烟和有牙周炎病史会影响种植体的成功率,但是在患者基因易感性和种植体周围组织炎症之间的关系上未达成统一。本文就白介素-1(IL-1)的基因多态性、牙周炎病史和吸烟因素与种植体周围炎相关性的研究进展作一综述。
Peri-implantitis are inflammatory lesions which effect the tissue near the implant in function.It is the main cause which dues to failed implant.Its clinical manifestations are fistula,bleeding or suppuration on probing,bone loss in the X-ray picture.There are many reasons for peri-implantitis,such as bacterial contamination,overloading.Besides biomechanical factors,genetic susceptibility,patients who have a history of periodontitis and smoking status are more at risk for peri-implant diseases.Most scholars think that smoking and a history of periodontitis may affect implant success rates,but they do not agree on the relationship between genotype and periimplantitis.This article is an overview about the polymorphisms in the interleukin-1（IL-1） gene,the history of periodontitis and smoking status,researching their relations with peri-implantitis.
出处
《国际口腔医学杂志》
CAS
2012年第3期353-356,共4页
International Journal of Stomatology
基金
广东省科技计划基金资助项目(2006B36006008)
关键词
种植体周围炎
基因
多态性
牙周炎
吸烟
peri-implantitis
gene
polymorphism
periodontitis
smoking
