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血透患者病毒感染状况初步调查 被引量:7

A study for viruses infection in patients undergoing hemodialysis
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摘要 目的与方法 :对 43例血液透析患者的五种肝炎相关病毒 (HBV、HCV、HEV、HGV和 CMV)标志物进行了检测。 结果 :以单项抗 - HCV Ig G检出率最高 ,达 5 8.1% (2 5 /4 3) ;抗 - CMV Ig M检出率次之 ,为 41.9% (18/4 3) ;其后依次为 HBs Ag30 .2 % (13/4 3) ,抗 - HCV Ig M2 5 .6 % (11/4 3) ,抗 - HBc18.6 % (8/2 5 ) ,抗 - HBs16 .3% (7/4 3) ,抗 - HGV Ig G 9.3% (4/4 3) ,HBe Ag 7.0 % (3/4 3) ,抗 HBe 4.7% (2 /4 3) ,抗 CMV- Ig G 4.7% (2 /4 3) ,抗 HEV- Ig G2 .3% (1/4 3) ;未测得抗 - HEV Ig M。HBV标志物总的阳性率为 80 % ,HCV为 73% ,CMV为 5 6 %。有 5例患者同时检出 HBV、HCV和 CMV标志物。 结论 :血液透析是肝炎相关病毒传播的一条重要途径 ,不仅可传播 HBV和HCV,而且还可传播 HEV和 HGV,临床上应引起对此类病毒感染的重视。 Objectives and Methods:In order to probe the prevalence of viruses infection in the blood of patients undergoing hemodialysis,the markers of 5 viruses: hepatitis B,C,E and G virus,and cytomegalovirus(CMV) were detected in the sera of 43 patients with continual hemodialysis. Results:The makers of all the 5 viruses were detected with various positive rates respectively.Single anti HCV IgG held the highest positive rate(58.1%,25/43).The anti CMV IgM took the next (49.1%,18/43).In order of the positive rate,the other markers were HBsAg(30.2%,13/43),anti HCV IgM(25.6%,11/43),anti HBe(18.5%,8/2),anti HBs(16.7%,7/43),HBeAg(7.0,3/43),anti HVG IgG(9.3%,4/43),anti HBe(4.7%,2/43),anti CMV IgG(4.7%,2/43),and anti HEV IgG(2.3%,1/43).No anti HEV IgM was found.In accordance with the variety of virus,the total positive rate of HBV markers took the first(80%),and those of HCV and CMV were 73% and 56% respectively.All the 3 viruses held more than 50% of positive rate.Five of the patients had markers of HBV,HCV and CMV simultaneously. Conclusions:Hemodialysis is an important access for transimission of viruses,especially hepatitis viruses.Not only HBV and HCV,but also HEV and HGV can be transmitted by hemodialysis.The monitoring and prevention for infection of these viruses should be taken seriously by clinicians.
出处 《医学研究生学报》 CAS 2000年第1期28-29,共2页 Journal of Medical Postgraduates
关键词 血液透析 肝炎病毒 巨细胞病毒 Hemodialysis Virus Hepatitis Cytomegalovirus
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