摘要
目的 进行临床试验来评价博宁治疗肿瘤骨转移引起的疼痛的疗效。方法 1996年 12月～ 1998年 6月治疗恶性肿瘤骨转移 40例。剂量为 3 0～ 60mg ,加入 0 9%生理盐水 5 0 0ml静脉滴注 ,维持 4～ 6小时。结果 总有效率为 75 % ( 3 0 /40 ) ,其中显效2 0 % ( 8/14 ) ,有效 5 5 % ( 2 2 /40 ) ,无效 2 5 % ( 10 /40 )。结论 博宁能有效地减轻骨转移引起的疼痛 ,其毒副反应轻微 ,一般体质差的病人也能耐受。
Objective This clinical trial is to evaluate the therapeutic efficacy of Bonin.Method From Dec.1996 to Jun.1998,40 cases with cancer related pain developed by bone metastases were treated with Bonin.Its dosage was that 30～60 mg of it was added in 500 ml of 0.9% NS,and then was given slowly by intravenous infusion for 4～6 hours.Result The total response rate was 75% (30/40).The completed response rate was 20% (8/11) and the partial response rate 25%(10/14).Conclusion Bonin can reduce the cancer related pain developed by bone metastases and its side effects are slight,so patients in poor conditions can receive it.
出处
《河南肿瘤学杂志》
2000年第2期91-92,共2页
Henan Journal of Oncology
