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双水平正压无创通气治疗急性中重度支气管哮喘的临床观察 被引量:2

Clinical observation of bi-level positive airway pressure noninvasive ventilation in acute moderate and severe bronchial asthma
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摘要 目的观察双水平正压无创通气治疗急性中重度支气管哮喘的临床疗效。方法将68例确诊为中重度哮喘急性发作的患者随机分为治疗组和对照组各34例。对照组给予常规治疗,治疗组在常规治疗基础上早期给予BiPAP治疗。比较两组患者治疗前后48h的血气分析(pH值、PaCO2、PaO2、SaO2)、肺功能(FEV1、FEV1/FVC%、PEF)及最终观察指标(治愈率、气管插管率、死亡率、平均住院日)。结果治疗组动脉血气指标与肺功能改善及最终观察指标均优于对照组(P<0.05)。结论双水平正压无创通气治疗可以明显改善患者的血气指标及肺功能,缩短住院时间,降低死亡率,是治疗急性中重度支气管哮喘的有效方法。 Objective To observe the clinical efficacy of BiPAP non-invasive mechanical ventilation treatment on patients with acute moderate and severe bronchial asthma. Methods Sixty eight patients diagnosed with moderate to severe acute asthma were randomly divided into treatment group and control group of 34 cases. Control group received conventional therapy, the treatment group were given early treatment based on the Bi-PAP therapy. Patients were compared before and after 48 h of blood gas analysis (pH, PaCO2, PaO2, SaO2), pulmonary function (FEV1, FEV1/FVC%, PEF) and the final observed indicators (cure rate, endotracheal intubation rate, mortality, average length of stay). Results Treatment group, arterial blood gas indicators and indicators of pulmonary function improvement and ultimately better than the control group observed (P0.05). Conclusion Bi-level positive airway pressure noninvasive ventilation can significantly improve the patient's blood gas analysis and pulmonary function, shorter hospital stay, reduce mortality, it is the treatment of acute moderate and severe bronchial asthma and effective way.
作者 张雪彦 赵晔
出处 《中国当代医药》 2012年第10期65-66,共2页 China Modern Medicine
关键词 支气管哮喘 双水平气道内正压通气 血气分析 肺功能 Blood gas analysis Bronchial asthma Bi-level positive airway pressure Pulmonary function
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