摘要
目的了解葡萄球菌感染的状况及对常用抗菌药物的耐药性,为临床用药提供参考。方法从该院儿科血培养中分离的葡萄球菌,用K-B法测定其对抗菌药物的敏感性,所有数据用WHONET5.4软件进行分析。结果共检出葡萄球菌136例,其中金黄色葡萄球菌19例,凝固酶阴性葡萄球菌117例。耐甲氧西林葡萄球菌的检出率为30.1%,万古霉素对葡萄球菌有很好的敏感性,未发现耐药菌株,对其他类型的抗菌药物均有不同程度的耐药。金黄色葡萄球菌的耐药率明显高于凝固酶阴性葡萄球菌。结论葡萄球菌对青霉素以及头孢类的耐药率太高而不宜用于临床治疗,治疗葡萄球菌引起的感染应根据药敏试验结果用药,并尽量减少万古霉素的使用,避免耐药菌株的产生。
Objective To investigate the status of infections and drug resistance to commonly used antibiotics of Staphylococcus to provide reference for clinical medication.Methods Staphylococcus,isolated from pediatric blood cultures,were detected for drug susceptibility by using K-B method.All data were analyzed by using WHONET5.4 software.Results 136 strains of Staphylococcus were isolated,among which 19 strains were Staphylococcus aureus and 117 strains were coagulase-negative Staphylococcus.The detection rate of meticillin-resistant Staphylococcus was 30.1%.No vancomycin-resistant Staphylococcus was detected.Clinical strains of Staphylococcus were variously resistant to other antibiotics.Drug resistance rate of Staphylococcus aureus was higher than coagulase-negative Staphylococcus.Conclusion Resistance rate of Staphylococcus aureus to penicillin and Cephalosporin was too high to be treated by these types of antibiotics.Treatment of Staphylococcus aureus infections should be based on susceptibility testing results,and the usage of vancomycin should be minimized to avoid the generation of drug-resistant strains.
出处
《国际检验医学杂志》
CAS
2012年第8期922-923,共2页
International Journal of Laboratory Medicine
关键词
葡萄球菌属
血培养
耐药性
Staphylococcus
blood culture
drug resistance
