摘要
SNP标记作为第三代分子标记,在分子遗传学、药物遗传学、法医学以及疾病的诊断和治疗等方面发挥着重要作用。介绍了SNP标记的定义与特点,对近年来以SNP标记为基础构建的Bin图谱、高通量SNP芯片分型以及以SNP标记为基础进行群体进化研究等三方面的应用概况进行了简述。提出了SNP标记现阶段发展存在的问题,并对其发展前景予以展望。
SNP （single nucleotide polymorphism） marker, as a molecular marker of the third generation, plays an important role in molecular genetics, pharmacogenetics, forensic medicine, diagnosis and treatment of diseases recently. In this paper, the definition and characteristics of SNP molecular marker were both introduced. And the application profiles of Bin map, high throughput SNP-chip classification and population evolution research on the basis of SNP molecular marker was presented respectively. Finally, the problems of SNP molecular marker at the present stage were proposed, and the prospects of SNP molecular marker was oredicted as well.
出处
《中国农学通报》
CSCD
2012年第12期154-158,共5页
Chinese Agricultural Science Bulletin
基金
国家科技重大专项"高产转基因水稻新品种培育"(2011ZX08001-004)
"863"计划"强优势水稻杂交种的创制与应用"(2011AA10A101)
