摘要
为探讨速尿与多巴胺对非酮症高渗性糖尿病昏迷（NHDC）患者少尿及肾功能的作用。本文在NHDC确诊后，在积极补充血容量,持续小剂量静脉滴注胰岛素的同时,给予持续静滴小剂量的速尿与多巴胺，每分钟0.5μg/kg的速度，8h后无效时，逐渐增加速尿的剂量（多巴胺不变），观察尿量及尿素氮的变化。结果：12例中8例于治疗后4h尿量逐渐增加，8h尿素氮逐渐下降，3例于8h无效，经增加速尿剂量后尿量增加,尿素氮下降。1例于12小时仍无效时，速尿剂量增至80mg静脉点滴，尿量增加、尿素氮下降。死亡2例，死于脑梗死及急性心肌梗死。结论：早期持续静脉点滴小剂量的速尿和多巴胺，能尽快促进利尿、缩短少尿期，加快肾功能恢复。
Objective To investigate the efficacy of early combin ative and continual droping furosemide and dopamine on uropenia and renal function of non-ketotic hyperosmotic diabetic coma［NHDC］.Methods When NHDC diagnosed,furosemide and dopamine are continuously dropped at the speed of 0.5μg/kg·min,while blood volum is supplied and minimal insulin is continuously dropped.If it is inefficient after 8 hours,gradually added the dose of thefurosemide ［dopamine is still dropped at the speed of 0.5μg/kg·min］.To study the urine volum and urea nitrogen.Results In 8 of the 12 cases, the urine volum is gradually increased after 4 hours,the urea nitrogen is gradually decreased after 8 hours;3 of the 12 cases are inefficient after 8 hours,but gradually added the dose of furosemide,the urine volum is increased and theurea nitrogen is decreased;1 of the 12 cases is still inefficient after 12 hours,by adding the dose of furosemide to 80mg,the urine volum is increased and the urea nitrogen is increased and the urea nitrogen is decreased.2 cases died of massive cerebral infarction and acute myocardial infarction.Conclusion Early continuously dropping minimal furosemide and dopamine can promote d iuresis,reduce oliguric stage,accelerate the recover of renal function.
出处
《交通医学》
2000年第1期12-13,共2页
Medical Journal of Communications
