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细菌感染与免疫在慢性阻塞性肺疾病发病和疾病进程中的作用 被引量:18

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摘要 慢性阻塞性肺疾病(COPD)的发病机制复杂,尚无有效药物阻止其进展。COPD的气道炎症反应为何不能随着戒烟而停止?为什么会产生激素抵抗?近年来,人们在试图回答以上问题的同时,更加关注:气道内是否存在细菌定植?如果潜在病毒感染可以放大烟草引起的炎症反应,那么定植细菌是否也具有作用?尽管在COPD患者肺组织和血清中发现了某些自身抗体,但是COPD是一种免疫性疾病吗?如果不是,这些抗体又起什么作用?
作者 沈宁 贺蓓
出处 《中华医学杂志》 CAS CSCD 北大核心 2012年第14期941-942,共2页 National Medical Journal of China
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参考文献10

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二级参考文献29

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