期刊文献+

布托啡诺复合罗哌卡因切口局部浸润对老年患者结肠术后疼痛的影响 被引量:6

下载PDF
导出
摘要 目的:探讨布托啡诺复合罗哌卡因切口局部浸润对老年患者结肠癌根治手术后疼痛的影响。方法:选择40例ASAII-III级择期行结肠癌根治手术的老年患者,随机分为布托啡诺、罗哌卡因组(B组)和罗哌卡因组(L组),手术结束后分别进行切口局部浸润。结果:术后4hVAS评分,两组无显著差异(P>0.05);术后8h、12h和24hVAS评分,B组均显著低于L组(P<0.05);B组术后24h舒芬太尼的用量明显低于L组(P<0.05);嗜睡发生率L组高于B组(χ2=7.025,P=0.00836)。结论:布托啡诺可有效延长局麻药切口局部浸润的作用时间,减轻老年患者结肠癌根治术后疼痛,减少镇痛药物的用量。
出处 《中国中西医结合外科杂志》 CAS 2012年第2期189-191,共3页 Chinese Journal of Surgery of Integrated Traditional and Western Medicine
  • 相关文献

参考文献6

  • 1White PF. The changing role of non-opioid analgesic techniques in the management of postoperative pain[J].Anesthesia and Analgesia,2005,(5 Suppl):S5-22. 被引量:1
  • 2Elvir-Lazo OL,White PF. Postoperative pain management after ambulatory surgery:role of multimodal analgesia[J].Anesthesiol Clin,2010,(02):217-224. 被引量:1
  • 3Detterbeck FC. Efficacy of methods of intercostal nerve blockade for pain relief after thoracotomy[J].Annals of Thoracic Surgery,2005,(04):1550-1559.doi:10.1016/j.athoracsur.2004.11.051. 被引量:1
  • 4郭婷,王德传,徐云根,刘景根.外周选择性kappa阿片受体激动剂的最新研究进展[J].药学进展,2006,30(3):104-108. 被引量:2
  • 5Mehta TR,Parikh BK,Bhosale GP. Post operative analgesia after incisional infiltration of bupivacaine v/s bupivacaine with buprenorphine[J].Journal of Anaesthesiology Clinical Pharmacology,2011,(02):211-214.doi:10.4103/0970-9185.81835. 被引量:1
  • 6Berg J O. Antibacterial properties of EMLA and lidocaine in wound tissue biopsies for culturing[J].Wound Repair and Regeneration,2006,(05):581-585. 被引量:1

二级参考文献19

  • 1Virendra K,Deqi G,Joel A,et al.Synthesis and evaluation of novel peripherally restricted κ opioid receptor agonists[J].Bioorg Med Chem Lett,2005,15(4):1091-1095. 被引量:1
  • 2Kumar V,Marella M A,Cortes B L,et al.Arylacetamides as peripherally restricted kappa opioid agonists[J].Bioorg Med Chem Lett,2000,10(10):2567-2570. 被引量:1
  • 3Binder W,Machelska H,Mousa S,et al.Analgesic and anti-inflammatory effects of two novel κ opioid peptides[J].Anesthesiology,2001,94:1033-1034. 被引量:1
  • 4Vanderah T W,Schteingart C D,Trojnar J.FE 200041 (D-Phe-D-Phe-D-Nle-D-Arg-NH2):a peripheral efficacious kappa opioid agonist with unprecedented selectivity[J].J Pharmacol Exp Ther,2004,307(1):326-333. 被引量:1
  • 5Paul A T,Pamela R S,William B,et al.Azepinone as a conformational constraint in the design of κ opioid receptor agonists[J].Bioorg Med Chem Lett,2004,14(22):5693-5697. 被引量:1
  • 6Virendra K,Deqi G.Amino acid conjugates as κ opioid receptor agonists[J].Bioorg Med Chem Lett,2005,15 (5):1279-1282. 被引量:1
  • 7Feng Y,Bryan L R.Salvinorin A:a novel and highly selective κ-opioid receptor agonist[J].Life Sci,2004,75(22):2615-2619. 被引量:1
  • 8Agnieszka K,Dariusz M.Non-peptide opioid receptor ligands-recent advances.PartⅠ-Agonists[J].Curr Med Chem,2002,9(17):1567-1589. 被引量:1
  • 9Sandner K A,Pan H L,Chen S R,et al.Effect of kappa opioid agonists on visceral nociception induced by uterine distension in rats[J].Pain,2002,96(1):13-22. 被引量:1
  • 10Michael K P.The Opioid receptor independent actions of kappa receptor agonist in cardiovascular system[J].Curr Pharm Des,2004,10(20):2429-2444. 被引量:1

共引文献1

同被引文献50

  • 1叶良德,朱萍华,彭莲红,周生智.布托啡诺与芬太尼复合罗哌卡因用于剖宫产术后硬膜外自控镇痛的效果分析[J].江西医药,2013,48(3):240-242. 被引量:4
  • 2Kainu JP,Sarvela J,Halonen P,et al. Continuous wound infusion with ropivacaine fails to provide adequate analgesia after caesare- an section [J]. Int J Obstet Anesth ,2012,21(2):119-124. 被引量:1
  • 3Cunha T M,Souza G R,Domingues A C,et al.Stimulation of periph- eral Kappa opioid receptors inhibits inflammatory hyperalgesia via activation of the PI3Kr/AKT/nNOS/NO signaling pathway [J]. Mol Pain,2012,8(10):1-8. 被引量:1
  • 4McMurrick PJ,Simpson PB,Wale RJ,et al.Continuous wound infu- sion of local anesthetic for the control of pain after elective abdomi- nal colorectal surgery [J]. Dis Colon Rectum, 2007, 50(12): 2158-2167. 被引量:1
  • 5Wada M, Kitayama M,Hashimoto H,et al. Brief reports: plasma rop- ivacaine concentrations after ultrasound-guided rectus sheath block in patients undergoing lower abdominal surgery [J]. Anesth Analg, 2012,114(1): 230-232. 被引量:1
  • 6Brown SL,Morrison AE.Local anesthetic infusion pump systems ad- verse events reported to the Food and Drug Administration [J]. An- esthesiology,2004,100 (5):1305-1307. 被引量:1
  • 7Donohoe CL,Nguyen M,Cook J,et al.Fast-track protocols in colorec- tal surgery [J]. Surg-J R Coil Surg E,2011,9(2):95-103. 被引量:1
  • 8Tsikitis VL,Holubar SD,Dozois EJ,et al.Advantages of fast-track re- covery after laparoscopic right hemicolectomy for colon cancer [J]. Surg Endosc,2010,24(8): 1911-1916. 被引量:1
  • 9Elvir-Lazo OL, White PF. Postoperative pain management after ambulatory surgery : role of multimodal analgesia [ J ]. Anesthesiol Clin, 2010, 28(2) :217-224. 被引量:1
  • 10Mehta TR, Parikh BK, Bhosale GP, et all Post operative analgesia after incisional infiltration of bupivacaine v/s bupivacaine with buprenorphine [ J ]. J Anaesthesiol Clin Pharmacol, 2011,27 (2) : 211-214. 被引量:1

引证文献6

二级引证文献22

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部