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更昔洛韦联合免疫球蛋白治疗小儿急性病毒性脑炎疗效观察 被引量:10

Clinical Efficacy of Ganciclovir Combined with Immunoglobulin in Treatment of Children with Acute Viral Encephalitis
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摘要 目的:探讨更昔洛韦联合免疫球蛋白(IVIG)在治疗小儿急性病毒性脑炎(AVE)中的作用。方法:对82例小儿AVE患者,按入院先后顺序随机分为观察组和对照组,每组41例。对照组给予更昔洛韦治疗,而观察组给予更昔洛韦联合IVIG治疗,对两组的临床疗效指标进行观察。结果:观察组在疗效及病程方面明显优于对照组,未见明显不良反应,组间比较差异有统计学意义(P<0.05)。结论:更昔洛韦联合IVIG是治疗急性病毒性脑炎的一种安全有效的措施,优于单用更昔洛韦治疗,具有重要价值,值得临床推广。 Objective:To explore the clinical efficacy of ganciclovir combined with immunoglobulin (IVIG) in treatment of children with acute viral encephalitis.Methods:According to the admission,82 children with acute viral encephalitis were randomly divided into observation and control group(n=41).The control group was given ganciclovir treatment,while the experimental group given ganciclovir IVIG therapy. On two groups of clinical effectiveness indexes were observed.Results:Efficacy and duration of the observation group is better than the control group.the difference was significant between groups (P〈0.05).The two groups showed no significant adverse effects.Conclusion:Ganciclovir combined with IVIG is a safe and effective measures to better than ganciclovir in treatment of children with acute viral encephalitis,have important clinical value and is worthy of promotion
作者 罗利华
出处 《中国医学创新》 CAS 2012年第11期39-40,共2页 Medical Innovation of China
关键词 免疫球蛋白 更昔洛韦 小儿 急性病毒性脑炎 Immunoglobulin Ganciclovir Children Acute viral encephalitis
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