摘要
目的 探讨新生儿高胆红素血症的围产期因素及其危险因素.方法 回顾分析住院治疗的1983 例新生儿临床资料,探讨高胆红素血症围产期因素,并采用多因素Logistic 回归方法分析新生儿胆红素血症围产期的危险因素.结果 新生儿高胆红素血症与新生儿性别、胎次、产妇年龄和分娩方式无明显相关性,而与新生儿胎龄、出生时体重、围产并发症、开始喂奶时间和胎粪排出时间相关;Logistic 回归分析以高胆红素血症为应变量、危险因素为待选变量,结果显示胎龄〈37 周、低出生体重、围产窒息、宫内窘迫、感染、出血、开始喂奶时间＞24h 和胎粪排出时间＞24h 为新生儿高胆红素血症围产期危险因素（P〈0.05 ）.结论 新生儿高胆红素血症围产期危险因素为胎龄〈37 周、低出生体重、围产窒息、宫内窘迫、感染、出血、开时喂奶时间＞24h 和胎粪排出时间＞24h.
Objective To study the pathogenesis and risk factors of hyperbilirubinemia in neonates during perinatal period. Methods 1983 neonates with hyperbilirubinemia from Jan 2007 to Jun 2010 were systematically reviewed. The pathogenesis and risk factors were analyzed with Logistic regression analysis. Results The differences of gender, parity, mother.s age and delivery mode were not statistics significant （ P〉0.05 ） , while they were in gestational age, birth weight, perinatal period＇s complication, initiation time of breastfeeding and time of first defecation （ P〈0.05 ） . Logistic regression analysis showed that gestational age 〈37w, low birth weight, suffocation, intrauterine distress, infection, bleeding, initiation time ofbreastfeeding 〉24h and time of first defecation 〉24h were risk factors for neonate hyperbilirubinemia （ P〈0.05 ） . Conclusion Gestational age 〈37w, low birth weight, suffocation, intrauterine distress, infection, bleeding, initiation time of breastfeeding 〉24h and time of first defecation 〉24h were risk factors for neonate hyperbilirubinemia.
出处
《浙江临床医学》
2012年第4期421-422,共2页
Zhejiang Clinical Medical Journal
