摘要
目的调查了解医院金黄色葡萄球菌(SAU)的临床标本分布及对抗菌药物的耐药性,为临床医师有效治疗感染性疾病选择药物提供参考依据。方法 SAU培养与鉴定按照卫生部《全国临床检验操作规程》,采用常规方法操作;药敏试验采用CLSI推荐的K-B法操作。依据CLSI 2008-2010年规则判断药敏结果。结果 SAU主要来自痰液/咽拭子,占33.6%,其次为脓液/分泌物,占27.3%;耐甲氧西林金黄色葡萄球菌(MRSA)的阳性率达到41.4%;SAU对多种临床常用抗菌药物产生了耐药性,对青霉素、苯唑西林、头孢西丁的耐药率为100.0%,对糖肽类抗菌药物保持了100.0%的抗菌活性。结论医院应加强临床医师抗菌药物使用管理,制止滥用抗菌药物的不良现象。
OBJECTIVE To investigate the distribution of Staphylococcus aureus（SAU） isolates in clinical specimen and antibiotic resistance status to provide evidence for clinically effective treatment of infective disease and use of antibiotics.METHODS Referring to the National Guide to Clinical Laboratory Procedure,SAU isolates were cultured and identified by routine methods.The antibiotic susceptibility testing was performed by K-B methods recommended by CLSI.And the results of drug susceptibility testings were read according to CLSI 2008-2010.RESULTS SAU isolates were mainly isolated from sputum or throat swab,accounting for 33.6%,followed by pus or secretions（27.3%）;the positive rate of MRSA reached to 41.4%;the resistance rates of SAU to penicillin,oxacillin,and cefoxitin were 100.0%.and the antibacterial activity against glycopeptide antibiotics reached 100.0%.CONCLUSION The hospital should strengthen administration of antibiotic use to restrain the abuse of antibiotics.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2012年第8期1714-1715,共2页
Chinese Journal of Nosocomiology
关键词
金黄色葡萄球菌
耐甲氧西林金黄色葡萄球菌
构成比
耐药性
Staphylococcus aureus
Methicillin-resistant Staphylococcus aureus
Constituent ratio
Antibiotics resistance
