摘要
目的采用超声心动图测量急性肺栓塞患者溶栓前后右心功能指标以评价溶栓效果。方法 80例急性肺栓塞患者均接受溶栓治疗。溶栓前和溶栓后24 h采用超声心动图检查患者右心室前壁厚度(RVAWT)、右心室舒张末期前后径(RVED)、主肺动脉内径(PAD)、右心室舒张期横径(RVDD)、右心房舒张期横径(RADD)、三尖瓣反流压差(TRPG)及肺动脉收缩压(SPAP)。结果 80例急性肺栓塞患者溶栓后RVAWT、RVED、PAD、RVDD、TRPG、SPAP分别为(4.23±1.02)mm、(26.20±3.01)mm、(26.67±2.36)mm、(36.23±4.36)mm、(31.68±2.33)mm Hg(1 mm Hg=0.133 kPa)、(37.52±3.20)mm Hg,较溶栓前的(7.56±1.22)mm、(31.78±3.26)mm、(29.44±2.20)mm、(40.20±5.01)mm、(48.98±3.80)mm Hg、(57.25±4.23)mm Hg均降低,且差异均有统计学意义(t值分别为3.01、2.78、2.35、2.75、2.98、3.55,P均<0.01或0.05);溶栓后患者RADD为(37.55±5.25)mm,与溶栓前的(38.25±4.25)mm比较差异无统计学意义(t=1.32,P=0.18)。结论超声心动图对急性肺栓塞患者溶栓前后右心功能评价有重要意义。溶栓治疗可改善急性肺栓塞患者右心功能。
Objective To evaluate the effect of thrombolysis through measuring right heart function index in patients with acute pulmonary embolism by ultrasound examination.Methods A total of 42 patients with acute pulmonary embolism were performed echocardiography before and after thrombolytic therapy.And the following indexed were measured,including right ventricular anterior wall thickness（RVAWT）,right ventricular end-diastolic（RVED）,pulmonary artery diameter（PAD）,right ventricular diastolic diameters（RVDD）,right atrium diastolic diameters（RADD）,tricuspid regurgitant pressure gradient（TRPG）and systolic pulmonary artery pressure（SPAP）.Results Between the value obtained before and then after thrombolysis,there were significant difference for RVAWT [（4.23±1.02）mm vs（7.56±1.22）mm）],RVED[（26.20±3.01）mm vs（31.78.23±3.26）mm）],PAD [（26.67±2.36）mm vs（29.44±2.20）mm],RVDD [（36.23±4.36）mm vs（40.20±5.01）mm],TRPG [（31.68±2.33） mm Hg vs（48.98±3.80） mm Hg,1 mm Hg=0.133 kPa],and SPAP [（37.52±3.20） mm Hg vs（57.25±4.23） mm Hg]（t=2.78,2.75,3.01,2.35,2.98,3.55,all P0.01 or P0.05）.While no significant difference was found for RADD[（37.55±5.25）mm vs（38.25±4.25）mm,t=1.32,P=0.18].Conclusion Echocardiogaphy has an important role for the evaluation of right heart function,and thrombolysis can improve right ventricular function in patients with acute pulmonary embolism.
出处
《中华医学超声杂志（电子版）》
2012年第4期36-38,共3页
Chinese Journal of Medical Ultrasound(Electronic Edition)
基金
国家"十五"科技攻关项目(2004BA703B07)
关键词
超声心动描记术
肺栓塞
心室功能
右
Ultrasonography Pulmonary embolism Ventricular function right
