摘要
以2,3-环氧丙基三甲基氯化铵(GTA)和壳聚糖为原料制备水溶性的壳聚糖季铵盐2-羟丙基三甲基氯化铵壳聚糖(HTCC),采用傅立叶红外光谱仪(FTIR谱图)和核磁共振仪(1H-NMR图谱)表征HTCC的结构,并进行抗菌性研究。结果表明,HTCC溶液和浸泡过HTCC的无纺布对大肠杆菌(Escherichia coli)和空肠弯曲菌(Campylobacter jejuni)有抑菌效果,其中对空肠弯曲菌的最低抑菌浓度(MIC)为8mg/mL,说明HTCC是一种具有应用潜力的高分子抗菌剂。
The water-soluble quaternary ammonium salt of 2-hydroxypropyhrimethyl ammonium chloride chitosan （HTCC） was successfully prepared by the reaction of chitosan with 2, 3-epoxypropyl trimethyl ammonium chloride （GTA）. The structure of HTCC was characterized by FFIR and ^1H NMR, and in vitro antimicrobial activities of HTCC were investigated systematically. The results indicated that the non-woven fabrics which had been immersed in HTCC solution demonstrated good antimicrobial activity against Escherichia coli and Campylobacter jejuni. The minimum inhibitory concentration （MIC） of HTCC solution against C. jejuni was 8 mg/mL. The results indicated that HTCC was a potential polymeric antimicrobial.
出处
《湖北农业科学》
北大核心
2012年第6期1136-1138,共3页
Hubei Agricultural Sciences
基金
2010年江苏省大学生实践创新训练计划项目
关键词
壳聚糖季铵盐
表征
抗菌性
HTCC
quaternary ammonium salt of chitosan
characterization
antimicrobial activities
2-hydroxypropyhrimethylammonium chloride chitosan（HTCC）
