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147株金黄色葡萄球菌耐药现状分析 被引量:8

Drug-resistance analysis of 147 strains of Staphylococcus aureus
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摘要 目的研究金黄色葡萄球菌(SAU)临床分离株的耐药性,为合理使用抗菌药物提供依据。方法采用VITEK2Compact型全自动微生物分析系统进行菌株鉴定和药敏试验,统计分析147株SAU的标本分布及耐药率。结果分泌物标本SAU检出率最高;耐甲氧西林金黄色葡萄球菌(MRSA)分离率达40.1%(59/147)。SAU对多种抗菌药物具有不同程度的耐药性,对呋喃妥因、利奈唑胺、奎努普汀/达福普汀、替加环素、万古霉素敏感率为100.0%。结论 SAU临床分离株耐药现状严重,MRSA的耐药情况更为严重,临床微生物实验室应加强MRSA监测工作。 Objective To analyze the drug-resistance of Staphylococcus aureus(SAU) isolated from clinical samples,and provide scientific evidence for reasonable usage of antibiotics.Methods Clinical distribution and drug-resistance for 147 strains of SAU were analyzed by VITEK 2 Compact analyzer.Results Mainly of the 147 strains of SAU were isolated from secretion specimens.The isolating of methicillin resistant Staphylococcus aureus(MRSA) was 40.1 %(59/147).Clinical isolates of SAU were resistant to antibiotics at different degree,with sensitivity rate of 100.0% to Nitrofurantoin,Linezolid,Quinupristin/Dalfopristin,Tigecycline and Vancomycin.Conclusion Drug-resistance status of SAU,especially MRSA,might be severe,and the monitoring of MRSA should be further strengthened in clinical microbiology laboratory.
出处 《国际检验医学杂志》 CAS 2012年第6期720-721,共2页 International Journal of Laboratory Medicine
关键词 金黄色葡萄球菌 耐甲氧西林金黄色葡萄球菌 耐药性 Staphylococcus aureus methicillin-resistant Staphylococcus aureus drug resistance
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