摘要
目的研究不同季节、不同年龄段妊娠期妇女TORCH抗体阳性率。方法采用化学发光免疫分析法对2861例孕妇进行血清TORCHIgM、IgG抗体筛查,包括弓形体(TOX)、风疹病毒(RUB)、巨细胞病毒(CMV)、单纯疱疹病毒(HSV)。结果 TORCHIgM筛查中,HSVIgM阳性率最高,为22.13%;TORCHIgG筛查中,HSV1/2IgG阳性率最高,为3.64%;>40～45岁年龄段HSVIgM阳性率为52.96%,高于其他年龄段(P<0.05);夏季TOXIgM阳性率为1.68%,高于冬、春季(P<0.05),秋季为0.75%,高于冬季(P<0.05),冬、春两季间差异无统计学意义(P>0.05)。结论 TORCHIgM及IgG阳性分别代表急性或既往感染,对于临床开展优生优育筛查具有非常重要的意义。本次调查为本地区妇女选择合适的年龄和季节怀孕提供了参考。
Objective To study TORCH screening results of pregnant woman in different season and age.Methods TORCH IgM and IgG in 2 861 cases of serum samples from pregnant women were detected by chemiluminescent,including Toxoplasma gondii（TOX）,Rubella（RUB）,Cytomegalovirus（CMV） and Herpes simplex virus（HSV）.Results The positive rate of HSV IgM was 22.13% and was the highest among TORCH IgM.The positive rate of HSV1/2 IgG was 3.64% and was the highest among TORCH IgG.The positive rate of HSV-IgM（52.96%） in 40-45 age group was significantly higher than other four age groups（P0.05）.In summer,the positive rate of TOX IgM was 1.68%,higher than in spring and winter（P0.05）.It was 0.75% in autumn,higher than in winter（P0.05）.There was no statistical difference of the positive rate of TOX IgM between winter and spring（P0.0）.Conclusion The positive of TORCH IgM and IgG could separately clue to the different diagnostic means and it could be great significant to promote birth quality and improve population quality.This conclusion could provide a valid reference for choice of pregnant.
出处
《国际检验医学杂志》
CAS
2012年第5期535-536,538,共3页
International Journal of Laboratory Medicine
关键词
产前诊断
TORCH筛查
化学发光免疫分析
孕妇
prenatal diagnosis
TORCH screening
chemiluminescence immunoassay
pregnant women
