摘要
目的探讨老年隐性高血压患者中心动脉压及增强指数与脉搏波传导速度(PWV)的相关性。方法选择临床诊断血压正常者250例,根据血压诊断标准分为血压正常(正常组)169例和隐性高血压(隐性组)81例,及高血压患者(高血压组)150例。监测24 h动态血压。并采用大动脉测量仪测量中心动脉压及其反射波;采用PWV测定仪测量颈桡动脉PWV(crPWV)。结果隐性组中心动脉收缩压、中心动脉舒张压、中心脉压、平均收缩压、平均舒张压、收缩末压、增强压、crPWV明显高于正常组,明显低于高血压组(P<0.05,P<0.01)。多元线性回归分析显示,中心动脉收缩压、中心脉压、LDL-C是crPWV的主要影响因素(β=0.268、β=0.313、β=0.311,P<0.01)。结论老年隐性高血压患者中心动脉压及增强指数明显升高,提示动脉弹性下降,中心动脉收缩压、中心脉压、LDL-C是影响动脉僵硬度的主要危险因素。
Objective To study the relation of central artery pressure and its augmentation index with pulse wave velocity（PWV） in aged patients with masked hypertension. Methods Two hundred and fifty individuals were divided into normal blood pressure group（n=169）,masked hypertension group（n=81）,and hypertension group（n=180） according to their blood pressure. Their 24 h dynamic blood pressure was monitored. Central artery pressure and its reflected wave were measured with a conductive artery device and carotid-radial pulse wave velocity（crPWV） was measured with a PWV device. Results The central artery systolic and diastolic pressure,central pulse pressure（CPP）,mean central systolic and diastolic pressure, end systolic pressure, augmented pressure and crPWV were significantly higher in masked hypertension group than in normal blood pressure group and significantly lower in masked hypertension group than in hypertension group（P〈0.05, P〈0. 01）. Multiple linear regression analysis showed that the central artery pressure,CPP,and LDL-C were the major risk factors for crPWV（β= 0. 268,0. 313, 0. 311, P〈 0.01）. Conclusion The central artery pressure and its augmentation index are significantly higher in aged patients with masked hypertension, indicating that decreased artery elasticity, central artery systolic pressure,CPP,and LDL-C are the major risk factors for arterial stiffness.
出处
《中华老年心脑血管病杂志》
CAS
北大核心
2012年第4期376-379,共4页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
基金
山东省科技发展计划项目(2005GG4202011)
关键词
高血压
脉搏
血压
动脉硬化
血压监测
便携式
hypertension
pulse
blood pressure
arteriosclerosis
blood pressure monitoring, ambulatory
