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冠心病患者hs-CRP和心肌损伤标志物检测的临床意义 被引量:2

The clinical significance of hs - CRP and myocardial injury marker detecting in coronary heart disease
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摘要 目的观察hs-CRP、eTn-T和CK-MB在冠心痛中的变化,探讨在冠心痛诊治中的临床应用价值。方法检测67例不同阶段冠心病患者血清hs-CRP、cTn-T和CK-MB的水平,与31例对照组比较并进行统计学分析。结果血清hs-CRP、cTn-T和CK-MB在急性心肌梗死(AMI)和不稳定型心绞痛(UAP)组均不同程度升高,显著高于稳定型心绞痛(SAP)和对照组,SAP组与对照组无显著性差异。结论在冠心病发生发展过程中存在炎性反应。cTn-T是心肌损伤的敏感指标,联合检测hs-CRP、cTn-T和CK-MB,具有重要临床诊断价值。 Objective Obseree the change of hs - CRP, cTn - T and CK - MB which exist in coronary heart disease; Enquire into the value of the clinical application in the course of diagnosing and treating coronary heart disease. Methods Examine the levels of sixty - seven coronary heart disease patients' sera- hs- CRP, cTn- T and CK- MB,who are in quite different levels; Compare those with the other thirty - one comparison groups; Do statistical analyses. Results The Sera - hs - CRP, cTn - T and CK - MB all rise to one degree or another, ex- isting in Acute Myocardial Infarction (AMI) and unstable Angina Pectoris( UAP), which exceed those notably existing in Stable Angina Pectoris (SAP) and the comparison groups. There is no remarkable difference between Group SA and the comparison group. Conclusions There exists an inflammatory response when Coronary Heart Disease happens and develops; cTn - T is a sensitive norm of Myocardial Injury; It's of Meat clinical diagnostic value to combine hs - CRP, cTn - T and CK - MB and examine them.
出处 《医学检验与临床》 2012年第1期10-11,共2页 Medical Laboratory Science and Clinics
关键词 冠心病 超敏C反应蛋白 肌钙蛋白T 肌酸激酶 Coronary Heart Disease High sensitivity C - reactive Protein(hs- CRP) Cardiac Troponin T(cTn- T) Creatine kinase(CK)
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