摘要
尽管角膜具有众多特殊的免疫赦免机制,但CD4+T细胞为主介导的角膜移植排斥反应仍是术后最常见的并发症。本文从高危角膜移植对免疫赦免状态的影响、角膜免疫机制的应答以及排斥反应的预防及治疗几个方面阐述角膜移植排斥反应的最新进展。(国际服科纵览,2012,36:31-35)
Although the cornea enjoys a remarkable degree of immune privilege, the CD4 + T cellmediated immune rejection remains the most common cause of keratoptasty failure. This review will focus on the latest progress of effect of high-risk corneal transplantation on immune privilege, the mechanism of corneal immune response, and prevention and treatment of corneal allografts rejection. (Int Rev Ophthalmol, 2012, 36: 31-35)
出处
《国际眼科纵览》
2012年第1期31-35,共5页
International Review of Ophthalmology
关键词
角膜移植术
穿透性
免疫排斥反应
免疫赦免
高危角膜
penetrating keratoplasty
immune rejection response
immune priviledge
high-risk cornea