摘要
用分子连接性的方法建立的氨噻肟类青霉素衍生物定量构效关系方程式,对药物分子结构进行定量判断。找出其最适一阶分子连接性指数~1X^v的范围,预示了该类化合物中其余同源物的活性。
The equations of quantitative structure- activity relationships of am-inothiazo penicillin derivatives have been established by the method of molecular connectivity and the molecular structures of medicines are determined quantitatively. The most suitable range of one order molecular connectivity index has been found and the activities of other similar compounds are predicted.
出处
《中国抗生素杂志》
CAS
CSCD
北大核心
1990年第6期418-420,共3页
Chinese Journal of Antibiotics
关键词
氨噻肟类
青霉素
衍生物
构效关系
Aminothtazo penicilin
Molecular connectivity
Molecular connectivity index
Structure-activity relationship
