摘要
目的探讨胰岛素强化治疗对老年脓毒症患者预后的影响。方法选择我院ICU病房2009年2月至2011年3月收治的老年脓毒症患者80例为研究对象,随机分为强化治疗组和常规治疗组。对比分析两组患者在降钙素原水平(PCT)、SOFA评分、ICU住院时间、低血糖发生率、多器官功能障碍综合征(MODS)发生率、28天病死率的差异。结果强化组外周血降钙素原水平、SOFA评分、ICU住院时间[(7.21±4.12)天vs(12.36±5.75)天,P<0.05]和MODS发生率(34.88%vs 48.65%,P<0.05)均明显低于常规组,强化组28天病死率略低于常规组(23.26%vs 27.03%),但差异无统计学意义(P>0.05)。结论胰岛素强化治疗可改善ICU老年脓毒症患者的病情,但对患者的死亡率无显著影响。
【Objective】 To explore effect of intensive insulin therapy on the prognosis of elderly patients with sepsis.【Methods】 From February 2009 to March 2011,80 elderly patients suffered from sepsis were selected from Department of Intensive Care Unit,Geriatric Hospital of Chengdu.They were randomly divided into two groups：intensive insulin treatment group and control group.Some parameters as follows were observed： the serum PCT level,the Sequential Organ Failure Assessment（SOFA） score,total days in ICU,the incidence of hypoglycemia,the incidence of multiple organ dysfunction syndrome（MODS） and the mortality.【Results】 Compared with the control group,patients in intensive insulin treatment group had significantly lower the serum PCT level and SOFA score,shorter ICU stay [（7.21 ±4.12） d vs（12.36 ±5.75） d,P0.05],lower complication rates of MODS（34.88% vs 48.65%,P0.05）,and mortality were decreased inappreciably.【Conclusion】 In intensive insulin therapy for ICU elderly patients with sepsis can improve the patients＇ condition,can＇t reduces the mortality.
出处
《中国医学工程》
2011年第10期26-27,共2页
China Medical Engineering
